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3C-Like Protease

Brain exposure of the ATM inhibitor AZD1390 in humans - a positron emission tomography (PET) study

714 views | Nov 21 2020

Aurelija Jucaite et al. found the potential of PET microdosing in predicting and guiding dose range and schedule for subsequent clinical studies. [Read the Full Post]

A phase I trial of temsirolimus and erlotinib in patients with refractory solid tumors

968 views | Nov 15 2020

Haeseong Park et al. found the he combination of temsirolimus and erlotinib at the RP2D was well tolerated, and the regimen resulted in prolonged disease stabilization in selected patients (NCT00770263). [Read the Full Post]