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TAZ Induces Migration of Microglia and Promotes Neurological Recovery After Spinal Cord Injury

112 views | Sep 09 2022

Xuyang Hu et al. found that TAZ mediated microglial migration to the edge of the lesion core, promoting the formation of microglial scars and functional recovery after SCI. [Read the Full Post]

Astrocytic YAP prevents the demyelination through promoting expression of cholesterol synthesis genes in experimental autoimmune encephalomyelitis

301 views | Oct 18 2021

Jingjing Zhang et al. found unrecognized functions of astrocytic YAP in the prevention of demyelination through promoting cholesterol synthesis in EAE, and revealed a novel pathway of YAP/HMGCS1 for cholesterol synthesis in EAE pathology. [Read the Full Post]

Resveratrol ameliorates lipopolysaccharide-induced anxiety-like behavior by attenuating YAP-mediated neuro-inflammation and promoting hippocampal autophagy in mice

374 views | Oct 22 2020

Qiuyun Tian et al.suggested that inhibition of YAP pathway could be a potential therapeutic target for anxiety-like behavior induced by neuro-inflammation. [Read the Full Post]