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Epigenetics Compound Library

Catalog No.L1900

A unique collection of 865 compounds with biological activity used for epigenetic research and associated assays.

96 well plates

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Cited by 345 Publications

Epigenetics Compound Library Contents

Description & Advantages

•A unique collection of 865 compounds with biological activity used for epigenetics research and associated assays 
 
•A valuable tool for chemical genomics, epigenetic target identification in pharmacogenomics, and other biological applications
 
• This library contains inhibitors of epigenetic enzymes including Histone Deacetylase (HDACs), SIRTs, Lysine demethylases, Histone Acetyltransferases (HATs), DNA Methyltransferase (Dnmts), and SIRTs activators
 
• Structurally diverse, medicinally active, and cell permeable
 
• Rich documentation with structure and customer reviews
 
• NMR and HPLC validated to ensure the highest purity

Product Details

Formulation 828 compounds pre-dissolved in 10mM DMSO, 16 compounds pre-dissolved in 10mM water, 20 compounds pre-dissolved in 2mM DMSO and 1 compound pre-dissolved in 2mM water
Container 96 Deep Well Plate Sealed With Aluminum Foil
Stability 12 months -20°C in DMSO
24 months -80°C in DMSO
Shipping Blue ice or dry ice

Case Studies using Selleck Compound Libraries

  • Application of GPCR Compound Library in liver cancer (This article was published in Nature (IF=43) and took about 15 months):

    Nature.2019;574(7777):268-272

  • Application of Kinase Inhibitor Library in colorectal cancer (This article was published in Nature Communications (IF=11) and took about 8 months):

    Nat Commun. 2019 16;10(1):2197

  • Application of FDA-approved Drug Library in antivirus (This article was published in Cell Research (IF=17) and took about 13 months):

    Cell Res. 2019;29(9):739-753

  • Application of FDA-approved Drug Library in metabolism (This article was published in Movement Disorders (IF=8) and took about 10 months):

    Mov Disord. 2019;34(3):323-334

  • Application of Epigenetics Compound Library in acute lymphoblastic leukemia (This article was published in Blood (IF=16) and took about 16 months):

    Blood. 2019 17;134(16):1323-1336

  • Application of Inhibitor Library in tumor immunology (This article was published in Cancer Immunol Res (IF=8.6) and took about 12 months):

    Cancer Immunol Res.2017;5(9):790-803

Epigenetics Compound Library Composition

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