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OX Receptor

Involvement of the tuberomammillary nucleus of the hypothalamus in the modulation of nociception and joint edema in a model of monoarthritis

282 views | Mar 15 2023

The study suggests that histaminergic projections from the TMN to the spinal cord play a role in the modulation of nociception and peripheral edema in a subacute monoarthritis model, and that the hypothalamus may trigger TMN activation via glutamate and orexin. [Read the Full Post]

Intrathecal Intermittent Orexin-A Causes Sympathetic Long-Term Facilitation and Sensitizes the Peripheral Chemoreceptor Response to Hypoxia in Rats

1748 views | Sep 12 2017

Kim SJ et al. revealed that the activation of spinal orexin receptors is critical to enhance peripheral chemoreceptor responses to hypoxia after AIH. [Read the Full Post]