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High-dose remifentanil exacerbates myocardial ischemia-reperfusion injury through activation of calcium-sensing receptor-mediated pyroptosis

121 views | Jan 15 2024

Short-term exposure to high radiofrequency exacerbates myocardial ischemia/reperfusion injury by upregulating calcium-sensing receptors, leading to increased cytosolic calcium levels, ROS production, and subsequent activation of the NLRP3 inflammasome, ultimately promoting pyroptotic cell death. [Read the Full Post]

Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury

1105 views | Sep 14 2018

Wang Z et al. indicated that upregulation of SULT2B1b might promote HOC proliferation and aggravate liver injury via the suppression of oxysterol-induced LXR activation in chemically induced mouse liver injury. [Read the Full Post]