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Proteases
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Others
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MALT

Integrating knowledge of protein sequence with protein function for the prediction and validation of new MALT1 substrates

428 views | Sep 07 2023

The bioinformatics-led substrate discovery workflow, GO-2-Substrates, successfully identified seven new MALT1 substrates, including TANK, TAB3, CASP10, ZC3H12D, ZC3H12B, CILK1, and ILDR2, expanding the known repertoire and providing valuable insights into the function of MALT1. [Read the Full Post]

Inhibition of MALT1 reduces ferroptosis in rat hearts following ischemia/reperfusion via enhancing the Nrf2/SLC7A11 pathway

190 views | May 15 2023

Inhibition of MALT1 can reduce I/R-induced myocardial ferroptosis through enhancing the Nrf2/SLC7A11 pathway, making MALT1 a potential therapeutic target for treating myocardial infarction. [Read the Full Post]