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SREBP

Visfatin-induced upregulation of lipogenesis via EGFR/AKT/GSK3β pathway promotes breast cancer cell growth

129 views | Jul 27 2023

Visfatin induces lipid synthesis and accumulation in breast cancer cells through activation of the EGFR/AKT/GSK3β pathway, promoting cell survival and proliferation. [Read the Full Post]

LATS-regulated nuclear-cytoplasmic translocation of SREBP2 inhibits hepatocellular carcinoma cell migration and invasion via epithelial-mesenchymal transition

116 views | Jul 27 2023

The study demonstrates that high expression of SREBP2 in hepatocellular carcinoma (HCC) is associated with poor prognosis and promotes HCC cell invasion and metastasis through the epithelial-mesenchymal transition (EMT) process, suggesting SREBP2 as a potential therapeutic target for HCC. [Read the Full Post]