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Positron Emission Tomography Imaging in Vasculitis

Systemic vasculitides comprise a group of autoimmune diseases affecting blood vessels. [18F]-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT) plays an important role in the diagnosis and therapeutic monitoring of vasculitides affecting large-sized and medium-sized vessels. FDG-PET/CT also provides complementary information to other vascular imaging tools. The resolution and sensitivity of newer generation scanners continues to increase, hereby improving the ability of FDG-PET/CT to accurately assess the full disease extent in patients with vasculitis. Novel tracers targeting specific immune cells will allow for more detailed detection of vascular infiltrates.

 

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Systemic vasculitides are a group of autoimmune diseases that affect blood vessels, and [18F]-fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT) plays an essential role in their diagnosis and therapeutic monitoring. This imaging modality has proven to be useful in the evaluation of vasculitis affecting large-sized and medium-sized vessels.

FDG-PET/CT provides complementary information to other vascular imaging tools and has shown significant potential in accurately assessing the full disease extent in patients with vasculitis. With the continuous advancements in the resolution and sensitivity of newer generation scanners, FDG-PET/CT is becoming an increasingly valuable tool in the diagnosis and management of vasculitis.

In addition, novel tracers that target specific immune cells are being developed, which will allow for more detailed detection of vascular infiltrates. This could potentially improve the accuracy of diagnosis and help to monitor the disease activity in patients with vasculitis more effectively.

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