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Taurocholic acid sodium salt hydrate

Synonyms: Sodium taurocholate hydrate

Taurocholic acid (Sodium taurocholate hydrate), a bile salt formed in the liver, is the product of conjugation of cholic acid with taurine that is involved in the emulsification of lipids. Its sodium salt is the chief ingredient of the bile of carnivorous animals.

Taurocholic acid sodium salt hydrate Chemical Structure

Taurocholic acid sodium salt hydrate Chemical Structure

CAS No. 345909-26-4

Purity & Quality Control

Batch: S513001 DMSO]100 mg/mL]false]]]false]]]false Purity: 98%
98

Taurocholic acid sodium salt hydrate Related Products

Biological Activity

Description Taurocholic acid (Sodium taurocholate hydrate), a bile salt formed in the liver, is the product of conjugation of cholic acid with taurine that is involved in the emulsification of lipids. Its sodium salt is the chief ingredient of the bile of carnivorous animals.
In vitro
In vitro The immunoregulation effect of TCA wasmediated through regulating both gene and protein expressions of TNF-α and IL-1β[2].
Cell Research Cell lines HTR-8/SVneo cells
Concentrations 0, 10, 50 and 100 μM
Incubation Time 6 h
Method

HTR-8/SVneo cells were sub-cultured in 6-well plates at a density of 2×105 cells per well with complete culture medium overnight, and then exposed to different concentrations of TCA (0 μM, 10 μM, 50 μM and 100 μM) for 6 h. Cells were harvested using trypsin, washed with PBS, resuspended in 1 ml binding buffer, and stained with 5 ml Annexin V-FITC and 5 μl PI at room temperature for 10 min. FITC and PI fluorescence was analyzed by flow cytometry.

Chemical Information & Solubility

Molecular Weight 537.68 (anhydrous basis) Formula

C26H45NO7S.xH2O.Na
CAS No. 345909-26-4 SDF Download Taurocholic acid sodium salt hydrate SDF
Smiles CC(CCC(=O)NCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C.O.[Na+]
Storage (From the date of receipt)

In vitro
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DMSO : 100 mg/mL ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
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