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Tea polyphenol

Tea polyphenols are chemical compounds such as flavanoids and tannins found naturally in tea. Several biological properties have been associated to tea polyphenols (TP), including antioxidant, anti-carcinogenic and antimicrobial activities.

Tea polyphenol Chemical Structure

Tea polyphenol Chemical Structure

CAS No. 84650-60-2

Purity & Quality Control

Batch: S510401 DMSO]100 mg/mL]false]Water]100 mg/mL]false]Ethanol]100 mg/mL]false Purity: 99.55%
99.55

Tea polyphenol Related Products

Biological Activity

Description Tea polyphenols are chemical compounds such as flavanoids and tannins found naturally in tea. Several biological properties have been associated to tea polyphenols (TP), including antioxidant, anti-carcinogenic and antimicrobial activities.
In vitro
In vitro Tea polyphenols are known as catechins. The catechins are subject to extensive biotransformation including methylation, glucuronidation, sulfation and ring-fission metabolism. (−)-epigallocatechin gallate (EGCG) is the major catechin in tea. Among tea catechins, EGCG is most effective in reacting with most reactive oxygen species[1].
In Vivo
In vivo The potential health effects of Tea polyphenols (catechins) depend on the amount consumed and on their bioavailability. Following oral administration to rats, tea catechins are absorbed intestinally. They are rapidly and extensively metabolized in rats[1].
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT00176566 Terminated
Oral Leukoplakia
University of Medicine and Dentistry of New Jersey|Rutgers The State University of New Jersey
 September 2003 Phase 2
NCT00176514 Terminated
Mucositis
University of Medicine and Dentistry of New Jersey|Rutgers The State University of New Jersey
 July 2000 Not Applicable

Chemical Information & Solubility

Molecular Weight Formula
CAS No. 84650-60-2 SDF Download Tea polyphenol SDF
Smiles C1C(C(OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 100 mg/mL ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 100 mg/mL

Ethanol : 100 mg/mL


Molecular Weight Calculator

In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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as vortex, ultrasound or hot water bath can be used to aid dissolving.

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