Ethylenediaminetetraacetic acid

Name: Ethylenediaminetetraacetic acid
Brand: Selleck Chemicals
SKU: S6350
Rating: 5 (4 reviews)

Synonyms: EDTA

Catalog No.S6350 Purity:99%

Ethylenediaminetetraacetic acid (EDTA) is a chelating agent commonly used in protein purification, to decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification and to inhibit protease activity. It can also decrease the formation of disulfide bonds and can also inhibit complement activation; protein protection in some immunoassays

Ethylenediaminetetraacetic acid Chemical Structure

CAS No. 60-00-4

Purity & Quality Control

Batch: S635001 4-Methylpyridine]5 mg/mL]true]DMSO]Insoluble]false]Water]Insoluble]false Purity: 99%

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Biological Activity

Description

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT06016088	Recruiting	Cystic Fibrosis Lung\|Respiratory Infections Recurrent Chronic\|Pseudomonas Aeruginosa	Respirion Pharmaceuticals Pty Ltd	April 1 2024	Phase 1\|Phase 2
NCT06153095	Recruiting	Systemic Lupus Erythematosus\|Lupus Nephritis	ImmPACT Bio	February 15 2024	Phase 1\|Phase 2
NCT05186311	Completed	Healthy\|Disease Chronic\|Acute Disease\|Sample Collection	Becton Dickinson and Company\|Babson Diagnostics Inc.	April 22 2022	--
NCT04893577	Enrolling by invitation	Herpes Simplex Oral	University of Utah	January 20 2022	Phase 2

References

Chemical Information & Solubility

Molecular Weight	292.24	Formula	C₁₀H₁₆N₂O₈
CAS No.	60-00-4	SDF	--
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

4-Methylpyridine : 5 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
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