L-Tryptophan

L-tryprophan is an essential amino acid that acts like a natural mood regulator that is necessary for normal growth in infants and for nitrogen balance in adults.

L-Tryptophan Chemical Structure

L-Tryptophan Chemical Structure

CAS No. 73-22-3

Purity & Quality Control

Batch: S398701 DMSO]11 mg/mL]false]]]false]]]false Purity: 99.28%
99.28

L-Tryptophan Related Products

Biological Activity

Description L-tryprophan is an essential amino acid that acts like a natural mood regulator that is necessary for normal growth in infants and for nitrogen balance in adults.
In Vivo
In vivo L-Tryptophan suppresses both serum glucose and insulin levels after oral glucose administration and inhibits glucose absorption from the intestine. It increases glucose-associated energy expenditure in rats in vivo. L-Tryptophan suppresses the rapid rise in blood glucose after a glucose-rich meal and lessens the burden of insulin secretion from β-cells. Oral administration of L-tryptophan is more effective than intraperitoneal injection[1].
Animal Research Animal Models Four-week-old male normal Sprague-Dawley rats
Dosages 62.5 mg/kg
Administration Oral administration
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06283706 Not yet recruiting
Healthy Aging
The Hospital for Sick Children|Canadian Institutes of Health Research (CIHR)
June 1 2024 Not Applicable
NCT06365801 Not yet recruiting
Irritable Bowel Syndrome
The Third Affiliated hospital of Zhejiang Chinese Medical University
April 2024 --
NCT06228352 Not yet recruiting
Ulcerative Colitis
Assistance Publique - Hôpitaux de Paris
March 2024 --
NCT06021535 Not yet recruiting
Aortic Stenosis|Gastrointestinal Microbiome|Metabolomics
Insel Gruppe AG University Hospital Bern
January 1 2024 --

Chemical Information & Solubility

Molecular Weight 204.23 Formula

C11H12N2O2

CAS No. 73-22-3 SDF --
Smiles C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 11 mg/mL ( (53.86 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


Molecular Weight Calculator

In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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