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Chlorogenic Acid

Cat.No.S2280

Chlorogenic acid (NSC 407296, Heriguard) is a hydroxycinnamic acid and a member of a family of naturally occurring organic compounds.
Chlorogenic Acid Chemical Structure

Chemical Structure

Molecular Weight: 354.31

Quality Control

Chemical Information, Storage & Stability

Molecular Weight 354.31 Formula

C16H18O9

Storage (From the date of receipt)
CAS No. 327-97-9 Download SDF Storage of Stock Solutions

Synonyms NSC 407296, Heriguard Smiles C1C(C(C(CC1(C(=O)O)O)OC(=O)C=CC2=CC(=C(C=C2)O)O)O)O

Solubility

In vitro
Batch:

DMSO : 71 mg/mL ( (200.38 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 71 mg/mL

Water : 18 mg/mL

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05757154 Completed
Healthy
Chalmers University of Technology|Paulig Group
March 31 2023 Not Applicable
NCT05547204 Completed
Skill Performance|Soccer Performance|Coffeeberry Effects
PepsiCo Global R&D
June 30 2022 Not Applicable
NCT03520452 Completed
Endothelial Dysfunction
Société des Produits Nestlé (SPN)
March 14 2018 Not Applicable
NCT02728349 Completed
Glioblastoma
Sichuan J.Z. Bio-chemical Science and Technology Development Co. Ltd|Beijing Shijitan Hospital Capital Medical University
April 12 2016 Phase 1
NCT02245204 Completed
Advanced Cancer
Sichuan J.Z. Bio-chemical Science and Technology Development Co. Ltd|Peking University Cancer Hospital & Institute
September 2014 Phase 1
NCT02136342 Terminated
Advanced Cancer
Chinese Academy of Medical Sciences|Sichuan J.Z. Bio-chemical Science and Technology Development Co. Ltd|ChineseAMS
May 2014 Phase 1

Tech Support

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