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Orcinol glucoside

Synonyms: Sakakin

Orcinol glucoside (OG, Sakakin) is an active constituent isolated from the rhizomes of Curculigo orchioides Gaertn. It shows potent antioxidative and anxiolytic activities without sedative effects.

Orcinol glucoside Chemical Structure

Orcinol glucoside Chemical Structure

CAS No. 21082-33-7

Purity & Quality Control

Batch: S382801 DMSO]57 mg/mL]false]]]false]]]false Purity: 98.92%
98.92

Orcinol glucoside Related Products

Biological Activity

Description Orcinol glucoside (OG, Sakakin) is an active constituent isolated from the rhizomes of Curculigo orchioides Gaertn. It shows potent antioxidative and anxiolytic activities without sedative effects.
In Vivo
In vivo Orcinol glucoside (OG) has an antidepressant effect in rats. OG (5, 10, and 20 mg/kg) increases the time spent in open arms and the number of entries into open arms in the elevated plus-maze test. OG (5 and 10 mg/kg) increases the number of head-dips in the hole-board test. At all tested doses, OG does not significantly affect the locomotion of mice in the open-field test. OG is anxiolytic agents without sedative effects[1].
Animal Research Animal Models Male CD-1 mice
Dosages 5, 10, or 20 mg/kg
Administration oral administration

Chemical Information & Solubility

Molecular Weight 286.28 Formula

C13H18O7
CAS No. 21082-33-7 SDF Download Orcinol glucoside SDF
Smiles CC1=CC(=CC(=C1)OC2C(C(C(C(O2)CO)O)O)O)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 57 mg/mL ( (199.1 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
Batch:

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

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