Morin Hydrate

Name: Morin Hydrate
Brand: Selleck Chemicals
SKU: S2325
Rating: 5 (4 reviews)

Synonyms: Aurantica

Catalog No.S2325 Purity:99.35%

Morin hydrate (Aurantica) is a flavonoid isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava).

Morin Hydrate Chemical Structure

CAS No. 6202-27-3

Purity & Quality Control

Batch: Purity: 99.35%

99.35

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Related Compound Libraries	FDA-approved Drug Library Natural Product Library Bioactive Compound Library-I Bioactive Compound Library-Ⅱ Express-Pick Library	Click to Expand

Biological Activity

Description	Morin hydrate (Aurantica) is a flavonoid isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava).

In vitro
In vitro	Morin hydrate is a flavonoid isolated from Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and from leaves of Psidium guajava (common guava). Morin hydrate as an antioxidant improves the survival time of rat glomerular mesangial cells which are attacked by oxyradicals. ^[1] Morin is also an effective hepatoprotector, both in cultured cells and in hepatic ischemia-reperfusion. ^[2] Morin hydrate is a new type of Islet Amyloid Polypeptide (IAPP) inhibitor, which may be used in type-2 diabetes and islet cell transplants. ^[3]

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT05231018	Unknown status	COVID-19\|Mental Health Impairment\|Telemedicine	Fondazione IRCCS Ca'' Granda Ospedale Maggiore Policlinico	October 28 2020	Not Applicable
NCT04653155	Unknown status	Insomnia	Hospital Authority Hong Kong	June 1 2020	Not Applicable
NCT04144231	Recruiting	Insomnia\|Schizophrenia\|Schizoaffective Disorder	Helsinki University Central Hospital\|University of Helsinki\|Finnish Institute for Health and Welfare\|Finnish Institute of Occupational Health	December 19 2019	Not Applicable

References

Chemical Information & Solubility

Molecular Weight	320.25	Formula	C₁₅H₁₀O₇ .H₂O
CAS No.	6202-27-3	SDF	Download Morin Hydrate SDF
Smiles	C1=CC(=C(C=C1O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O.O
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 64 mg/mL ( (199.84 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 2 mg/mL

Water : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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