PMPA tetrasodium salt

Name: PMPA tetrasodium salt
Brand: Selleck Chemicals
SKU: S0189
Rating: 5 (1 reviews)

Synonyms: PMPA sodium

Catalog No.S0189 Purity:99.83%

PMPA tetrasodium salt (PMPA sodium) is a potent and selective inhibitor of glutamate carboxypeptidase 2 (GCP II/NAALADase).

PMPA tetrasodium salt Chemical Structure

CAS No. 373645-42-2

Purity & Quality Control

Batch: S018901 Water]63 mg/mL]false]DMSO]Insoluble]false]Ethanol]Insoluble]false Purity: 99.83%

99.83

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Biological Activity

Description

PMPA tetrasodium salt (PMPA sodium) is a potent and selective inhibitor of glutamate carboxypeptidase 2 (GCP II/NAALADase).

Targets

GCP II ^[1]

References

[1] Callum Hicks, et al. Psychopharmacology (Berl). 2017 Jun;234(11):1671-1681.

Chemical Information & Solubility

Molecular Weight	314.05	Formula	C₆H₇Na₄O₇P
CAS No.	373645-42-2	SDF	--
Smiles	C(CC(=O)O)C(CP(=O)(O)O)C(=O)O
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

Water : 63 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble

Molecular Weight Calculator

In vivo
Batch:

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In vivo Formulation Calculator

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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