1,2-Propanediol

Synonyms: 1,2-Dihydroxypropane, Propylene glycol, Methyl ethyl glycol

1,2-Propanediol (1,2-Dihydroxypropane, Propylene glycol, Methyl ethyl glycol) is a synthetic liquid substance that is commonly used as an excipient in a variety of drugs and it is also authorised in food products and cosmetics.

1,2-Propanediol Chemical Structure

1,2-Propanediol Chemical Structure

CAS No. 57-55-6

Purity & Quality Control

1,2-Propanediol Related Products

Biological Activity

Description 1,2-Propanediol (1,2-Dihydroxypropane, Propylene glycol, Methyl ethyl glycol) is a synthetic liquid substance that is commonly used as an excipient in a variety of drugs and it is also authorised in food products and cosmetics.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT04646135 Unknown status
Analgesia
Bambino Gesù Hospital and Research Institute|Ministero della Salute Italy|University College London
December 2020 Phase 2
NCT03605641 Completed
Second Hand Tobacco Smoke
Juul Labs Inc.|Inflamax Research Incorporated
September 17 2018 Not Applicable
NCT00535470 Completed
Mycosis Fungoides
Yaupon Therapeutics
July 2007 Phase 2

Chemical Information & Solubility

Molecular Weight 76.09 Formula

C3H8O2

CAS No. 57-55-6 SDF --
Density 1.036 g/mL at 25 °C
Smiles CC(CO)O
Storage (From the date of receipt) 2 years -20°C liquid

In vitro
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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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