DL-Citrulline

Name: DL-Citrulline
Brand: Selleck Chemicals
SKU: S5124
Rating: 5 (1 reviews)

Synonyms: Citrulline

Catalog No.S5124 Purity:98%

L-Citrulline (Citrulline, Cit) is a naturally occurring nonessential amino acid which is the key intermediate in the urea cycle.

DL-Citrulline Chemical Structure

CAS No. 627-77-0

Purity & Quality Control

Batch: S512401 Water]35 mg/mL]false]DMSO]Insoluble]false]]]false Purity: 98%

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Related Compound Libraries	FDA-approved Drug Library Natural Product Library Bioactive Compound Library-I Express-Pick Library	Click to Expand

Biological Activity

Description	L-Citrulline (Citrulline, Cit) is a naturally occurring nonessential amino acid which is the key intermediate in the urea cycle.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT06207461	Not yet recruiting	Traditional Chinese Acupoint Message\|Intestinal Barrier\|Gastrointestinal Dysfunction	Wuhan Union Hospital China	February 15 2024	--
NCT05636397	Recruiting	BPD - Bronchopulmonary Dysplasia\|Pulmonary Hypertension\|NEC	The Hospital for Sick Children	November 1 2023	Not Applicable
NCT06092476	Not yet recruiting	Diabetes Mellitus Type 2	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)\|Fractyl Health Inc.	November 1 2023	Not Applicable
NCT06025383	Recruiting	Menopause\|Hypertension	Texas Tech University	July 20 2023	Not Applicable
NCT05590117	Enrolling by invitation	Colo-rectal Cancer\|Neuropathy;Peripheral\|Mucositis	Tanta University	October 11 2022	Early Phase 1

Chemical Information & Solubility

Molecular Weight	175.19	Formula	C₆H₁₃N₃O₃
CAS No.	627-77-0	SDF	Download DL-Citrulline SDF
Smiles	C(CC(C(=O)O)N)CNC(=O)N
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

Water : 35 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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