Home Others Others Dansylcadaverine (Monodansyl cadaverine) For research use only.

Dansylcadaverine (Monodansyl cadaverine)

Synonyms: MDC, Monodansyl cadaverine

Dansylcadaverine (Monodansyl cadaverine, MDC) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine, a high affinity substrate of transglutaminases, can block the receptor-mediated endocytosis of many ligands.

Dansylcadaverine (Monodansyl cadaverine) Chemical Structure

Dansylcadaverine (Monodansyl cadaverine) Chemical Structure

CAS No. 10121-91-2

Purity & Quality Control

Batch: E045101 DMSO]67 mg/mL]false]Ethanol]8 mg/mL]false]Water]Insoluble]false Purity: 98.95%
98.95

Dansylcadaverine (Monodansyl cadaverine) Related Products

Biological Activity

Description

Dansylcadaverine (Monodansyl cadaverine, MDC) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine, a high affinity substrate of transglutaminases, can block the receptor-mediated endocytosis of many ligands.
In vitro
In vitro

Dansylcadaverine is an autofluorescent compound used for the labeling of autophagic vacuoles, which is able to serve as a substrate for transglutaminases and to block competitively the crosslinking of fibrin molecules.[3]
Cell Research Cell lines MCF7 cells
Concentrations 50 mM
Incubation Time 15 min
Method

MCF7 cells (2.4 ×104 ) are seeded into 35 mm plates. After 24 h incubation, CuO NPs are added with an increasing concentration in the presence or absence of 3-MA for different time periods. The cells are then incubated with 50 mM monodansylcadaverine at 37℃ for 15 min and washed with 1×PBS three times with 5 min interval. Finally, the cells are observed under a fluorescence microscope.

Chemical Information & Solubility

Molecular Weight 335.46 Formula

C17H25N3O2S
CAS No. 10121-91-2 SDF --
Smiles CN(C)C1=CC=CC2=C(C=CC=C12)[S](=O)(=O)NCCCCCN
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 67 mg/mL ( (199.72 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 8 mg/mL

Water : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Dansylcadaverine (Monodansyl cadaverine) | Dansylcadaverine (Monodansyl cadaverine) supplier | purchase Dansylcadaverine (Monodansyl cadaverine) | Dansylcadaverine (Monodansyl cadaverine) cost | Dansylcadaverine (Monodansyl cadaverine) manufacturer | order Dansylcadaverine (Monodansyl cadaverine) | Dansylcadaverine (Monodansyl cadaverine) distributor