Vanillyl Alcohol

Name: Vanillyl Alcohol
Brand: Selleck Chemicals
SKU: S3859
Rating: 5 (1 reviews)

Synonyms: 4-Hydroxy-3-methoxybenzyl alcohol, Vanillin alcohol, Vanillic alcohol, 3-Methoxy-4-hydroxybenzyl alcohol, 4-Hydroxy-3-methoxybenzenemethanol

Catalog No.S3859 Purity:99.75%

Vanillyl alcohol (4-Hydroxy-3-methoxybenzyl alcohol, Vanillin alcohol, Vanillic alcohol, 3-Methoxy-4-hydroxybenzyl alcohol), derived from vanillin, is used to flavor food.

Vanillyl Alcohol Chemical Structure

CAS No. 498-00-0

Purity & Quality Control

Batch: S385901 DMSO]30 mg/mL]false]]]false]]]false Purity: 99.75%

99.75

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Biological Activity

Description	Vanillyl alcohol (4-Hydroxy-3-methoxybenzyl alcohol, Vanillin alcohol, Vanillic alcohol, 3-Methoxy-4-hydroxybenzyl alcohol), derived from vanillin, is used to flavor food.

In vitro
In vitro	Vanillyl alcohol (VA) attenuates the elevation of reactive oxygen species (ROS) levels, decreases in the Bax/Bcl-2 ratio and poly (ADP-ribose) polymerase proteolysis. It protects dopaminergic MN9D cells against MPP+-induced apoptosis by relieving oxidative stress and modulating the apoptotic process^[2]. VA has a suppressive effect on ferric chloride-induced lipid peroxidation in rat brains in vitro^[3].
Cell Research	Cell lines	MN9D Cells
	Concentrations	1, 10, 20 μM
	Incubation Time	4 h
	Method	MN9D cells are pretreated with various concentrations (10, 100, 200 μg/mL) of GE and 1, 10, 20 μM vanillyl alcohol for 4 h before incubation in medium containing 25 μM MPP+. The control cells are treated with the same medium without drugs.

In Vivo
In vivo	vanillyl alcohol possesses anti-angiogenic, anti-inflammatory, and anti-nociceptive activities. Vanillyl alcohol contains both anticonvulsive and suppressive effects on seizures and lipid peroxidation induced by ferric chloride in rats^[1].
Animal Research	Animal Models	Male ICR mice
	Dosages	3, 10, or 30 mg/kg
	Administration	oral

References

Chemical Information & Solubility

Molecular Weight	154.16	Formula	C₈H₁₀O₃
CAS No.	498-00-0	SDF	--
Smiles	COC1=C(C=CC(=C1)CO)O
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 30 mg/mL ( (194.6 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

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In vivo
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