trans-Aconitic acid

Name: trans-Aconitic acid
Brand: Selleck Chemicals
SKU: S3090
Rating: 5 (1 reviews)

Synonyms: TAA

Catalog No.S3090 Purity:99.57%

trans-Aconitic acid (TAA) is an abundant constituent in the leaves of Echinodorus grandiflorus, a medicinal plant used to treat rheumatoid arthritis in Brazil.

trans-Aconitic acid Chemical Structure

CAS No. 4023-65-8

Purity & Quality Control

Batch: S309001 DMSO]35 mg/mL]false]Water]35 mg/mL]false]Ethanol]35 mg/mL]false Purity: 99.57%

99.57

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Biological Activity

Description	trans-Aconitic acid (TAA) is an abundant constituent in the leaves of Echinodorus grandiflorus, a medicinal plant used to treat rheumatoid arthritis in Brazil.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT05134740	Recruiting	Hodgkins Lymphoma\|Non Hodgkins Lymphoma	Baylor College of Medicine\|Center for Cell and Gene Therapy Baylor College of Medicine	April 2024	Phase 1
NCT06353607	Recruiting	Acute Aortic Dissection\|Thoracic Aortic Aneurysm	University Hospital Basel Switzerland	April 8 2024	--
NCT06286358	Recruiting	Aortic Valve Disease\|Aortic Aneurysm	Université Libre de Bruxelles\|Erasme University Hospital	March 7 2024	--
NCT06208514	Recruiting	Fibromyalgia	University of Michigan	March 4 2024	Not Applicable
NCT05812027	Recruiting	Head and Neck Cancer\|Cervical Cancer\|Non Small Cell Lung Cancer\|Melanoma\|Ovarian Cancer\|HPV16 Related Cancers	TScan Therapeutics Inc.	June 26 2023	--
NCT05844618	Recruiting	Atopic Dermatitis	Innovaderm Research Inc.	May 9 2023	Phase 4

References

[1] Diego Pinto de Oliveira, et al. Biomed Pharmacother. 2018 Mar;99:87-95.

Chemical Information & Solubility

Molecular Weight	174.11	Formula	C₆H₆O₆
CAS No.	4023-65-8	SDF	--
Smiles	OC(=O)C\C(=C/C(O)=O)C(O)=O
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 35 mg/mL ( (201.02 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 35 mg/mL

Ethanol : 35 mg/mL

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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