Tranexamic Acid

Name: Tranexamic Acid
Brand: Selleck Chemicals
SKU: S1875
Rating: 5 (2 reviews)

Synonyms: Transamin

Catalog No.S1875 Purity:97%

Tranexamic Acid(Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.

Tranexamic Acid Chemical Structure

CAS No. 1197-18-8

Purity & Quality Control

Purity: >97%

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Biological Activity

Description	Tranexamic Acid(Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT06149091	Recruiting	Iatrogenic Endobronchial Bleeding	China-Japan Friendship Hospital\|The Second Affiliated Hospital of Harbin Medical University\|The First Affiliated Hospital of Nanchang University	December 1 2023	Early Phase 1
NCT06097611	Not yet recruiting	Tranexamic Acid Effect in Pediatric Polytraumatized Patients	Assiut University	November 2023	Early Phase 1

Chemical Information & Solubility

Molecular Weight	157.21	Formula	C₈H₁₅NO₂
CAS No.	1197-18-8	SDF	Download Tranexamic Acid SDF
Smiles	C1CC(CCC1CN)C(=O)O
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

Water : 31 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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