Thioacetamide

Name: Thioacetamide
Brand: Selleck Chemicals
SKU: E0156
Rating: 5 (1 reviews)

Synonyms: TAA

Catalog No.E0156 Purity:99.94%

Thioacetamide (TAA) is a hepatotoxin frequently used for experimental purposes which produces centrilobular necrosis after a single dose administration.

Thioacetamide Chemical Structure

CAS No. 62-55-5

Purity & Quality Control

Batch: E015601 DMSO]15 mg/mL]false]Water]15 mg/mL]false]Ethanol]15 mg/mL]false Purity: 99.94%

99.94

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Biological Activity

Description	Thioacetamide (TAA) is a hepatotoxin frequently used for experimental purposes which produces centrilobular necrosis after a single dose administration.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT05134740	Recruiting	Hodgkins Lymphoma\|Non Hodgkins Lymphoma	Baylor College of Medicine\|Center for Cell and Gene Therapy Baylor College of Medicine	April 2024	Phase 1
NCT06353607	Recruiting	Acute Aortic Dissection\|Thoracic Aortic Aneurysm	University Hospital Basel Switzerland	April 8 2024	--
NCT06286358	Recruiting	Aortic Valve Disease\|Aortic Aneurysm	Université Libre de Bruxelles\|Erasme University Hospital	March 7 2024	--
NCT06208514	Recruiting	Fibromyalgia	University of Michigan	March 4 2024	Not Applicable
NCT05812027	Recruiting	Head and Neck Cancer\|Cervical Cancer\|Non Small Cell Lung Cancer\|Melanoma\|Ovarian Cancer\|HPV16 Related Cancers	TScan Therapeutics Inc.	June 26 2023	--
NCT05844618	Recruiting	Atopic Dermatitis	Innovaderm Research Inc.	May 9 2023	Phase 4

References

[1] Pavla Staňková, et al. Toxicol In Vitro . 2010 Dec;24(8):2097-103.

Chemical Information & Solubility

Molecular Weight	75.13	Formula	C₂H₅NS
CAS No.	62-55-5	SDF	--
Smiles	CC(N)=S
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 15 mg/mL ( (199.65 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 15 mg/mL

Ethanol : 15 mg/mL

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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