Polyethylenimine

Name: Polyethylenimine
Brand: Selleck Chemicals
SKU: E4019
Rating: 5 (1 reviews)

Synonyms: PEI

Catalog No.E4019

Polyethylenimine (PEI) is a hydrophilic cationic polymer that acts as a low toxicity and efficient gene vector.

Polyethylenimine Chemical Structure

CAS: 9002-98-6

Purity & Quality Control

Polyethylenimine Related Products

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Biological Activity

Description	Polyethylenimine (PEI) is a hydrophilic cationic polymer that acts as a low toxicity and efficient gene vector.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT05644821	Recruiting	Prostate Cancer	Heinrich-Heine University Duesseldorf\|Marienhospital Herne\|University Hospital Essen\|University Hospital Bonn\|Klinikum Dortmund gGbmH\|University Hospital Muenster\|University Hospital of Cologne\|University of Cologne\|Techniker Krankenkasse\|Deutsche Krebsgesellschaft e.V.	August 1 2023	Not Applicable
NCT05804409	Not yet recruiting	Pancreatic Exocrine Insufficiency	Assiut University	June 2023	--
NCT05266963	Enrolling by invitation	Type 1 Diabetes	Vanderbilt University Medical Center	September 2 2022	Early Phase 1
NCT05244174	Recruiting	Pancreatic Neoplasm Malignant Head Primary\|Pancreatic Exocrine Insufficiency	Hospital Clinico Universitario de Santiago	January 25 2022	Not Applicable
NCT04548778	Recruiting	Exocrine Pancreatic Insufficiency	Bühlmann Laboratories AG	November 1 2020	--

References

[1] Wen Y, et al. Bioconjug Chem. 2009 Feb;20(2):322-32.

Chemical Information & Solubility

Molecular Weight	43.07	Formula	(C₂H₅N)_x
CAS No.	9002-98-6	SDF	--
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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