Menthol

Name: Menthol
Brand: Selleck Chemicals
SKU: E4112
Rating: 5 (1 reviews)

Catalog No.E4112

Menthol is a natural analgesic compound that causes a feeling of coolness due to stimulation of ‘cold’ receptors by inhibiting Ca++ currents of neuronal membranes.

Menthol Chemical Structure

CAS No. 1490-04-6

Purity & Quality Control

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Biological Activity

Description	Menthol is a natural analgesic compound that causes a feeling of coolness due to stimulation of ‘cold’ receptors by inhibiting Ca++ currents of neuronal membranes.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT05785026	Recruiting	Dyspnea\|Chronic Obstructive Pulmonary Disease	KU Leuven	January 1 2023	Not Applicable
NCT05499377	Recruiting	Tobacco Use	Virginia Commonwealth University\|National Institute on Drug Abuse (NIDA)	November 28 2022	Not Applicable
NCT04351594	Unknown status	Knee Osteoarthritis	Memorial University of Newfoundland	November 1 2020	Phase 2\|Phase 3
NCT03953508	Completed	Smoking Cigarette	University of Oklahoma	August 1 2020	Not Applicable

References

[1] Galeotti N, et al. Neurosci Lett. 2002 Apr 12;322(3):145-8.

Chemical Information & Solubility

Molecular Weight	156.27	Formula	C₁₀H₂₀O
CAS No.	1490-04-6	SDF	Download Menthol SDF
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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