Linoleic acid

Synonyms: 9,12-octadecadienoic acid

Linoleic acid (9,12-octadecadienoic acid) is an essential fatty acid used in the biosynthesis of arachidonic acid and found in the lipids of cell membranes.,

Linoleic acid Chemical Structure

Linoleic acid Chemical Structure

CAS No. 60-33-3

Purity & Quality Control

Linoleic acid Related Products

Biological Activity

Description Linoleic acid (9,12-octadecadienoic acid) is an essential fatty acid used in the biosynthesis of arachidonic acid and found in the lipids of cell membranes.,
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06274788 Not yet recruiting
Parenteral Nutrition Associated Liver Disease (PNALD)|Essential Fatty Acid Deficiency|Malnutrition|Pediatric ALL
Fresenius Kabi
May 1 2024 Phase 4
NCT05556967 Completed
Adherence Patient
University of Mississippi Medical Center|University of Mississippi National Center for Natural Products Research|National Center for Complementary and Integrative Health (NCCIH)
August 9 2023 Not Applicable
NCT05788588 Active not recruiting
Parenteral Nutrition
Fujian Shengdi Pharmaceutical Co. Ltd.
April 28 2023 Phase 3
NCT05242224 Recruiting
Growth Disorders|Malnutrition Fetal|Stunting|Development; Delayed Malnutrition|Nutrition Disorder Fetal|Maternal Nutritional Disorders Affecting Fetus or Newborn
Washington University School of Medicine|St. Louis Children''s Hospital|St. Louis University|Children''s Discovery Institute|Universidad San Francisco de Quito
January 5 2022 Not Applicable

Chemical Information & Solubility

Molecular Weight 280.45 Formula

C18H32O2

CAS No. 60-33-3 SDF --
Density 0.902 g/mL at 25 °C
Smiles CCCCCC=CCC=CCCCCCCCC(=O)O
Storage (From the date of receipt) 2 years -20°C(in the dark) liquid

In vitro
Batch:

DMSO : 56 mg/mL ( (199.67 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 56 mg/mL

Water : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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