L-carnosine

Name: L-carnosine
Brand: Selleck Chemicals
SKU: S5226
Rating: 5 (1 reviews)

Synonyms: Karnozin

Catalog No.S5226 Purity:99.95%

L-carnosine (Karnozin) is an antioxidant naturally found in skeletal muscle, brain tissue, and the heart that protects cells against oxidative stress.

L-carnosine Chemical Structure

CAS No. 305-84-0

Purity & Quality Control

Batch: S522601 Water]45 mg/mL]false]DMSO]Insoluble]false]]]false Purity: 99.95%

99.95

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Biological Activity

Description	L-carnosine (Karnozin) is an antioxidant naturally found in skeletal muscle, brain tissue, and the heart that protects cells against oxidative stress.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT05860088	Recruiting	Muscle Weakness\|Muscle; Fatigue Heart\|Older Adults	Indiana University	July 10 2023	Not Applicable
NCT05371145	Recruiting	Peripheral Arterial Disease	University of Louisville	March 1 2023	Phase 1\|Phase 2
NCT04949607	Completed	Brain Injury Chronic\|Brain Injuries Traumatic	Centre for Neuro Skills\|University of Texas	July 28 2021	Not Applicable

Chemical Information & Solubility

Molecular Weight	226.23	Formula	C₉H₁₄N₄O₃
CAS No.	305-84-0	SDF	--
Smiles	C1=C(NC=N1)CC(C(=O)O)NC(=O)CCN
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

Water : 45 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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