Iohexol

Name: Iohexol
Brand: Selleck Chemicals
SKU: S4531
Rating: 5 (1 reviews)

Synonyms: Omnipaque

Catalog No.S4531 Purity:99.81%

Iohexol (Omnipaque) is a radiographic contrast agent that can be used as an exogenous filtration marker for accurate glomerular filtration rate (GFR) estimates.

Iohexol Chemical Structure

CAS No. 66108-95-0

Purity & Quality Control

Batch: S453101 DMSO]100 mg/mL]false]Water]100 mg/mL]false]Ethanol]100 mg/mL]false Purity: 99.81%

99.81

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Related Compound Libraries	FDA-approved Drug Library Natural Product Library Bioactive Compound Library-I Bioactive Compound Library-Ⅱ Express-Pick Library	Click to Expand

Biological Activity

Description	Iohexol (Omnipaque) is a radiographic contrast agent that can be used as an exogenous filtration marker for accurate glomerular filtration rate (GFR) estimates.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT05136963	Not yet recruiting	Kidney Function Test	Centre Hospitalier Universitaire de Saint Etienne	June 2024	Phase 1
NCT06244758	Recruiting	Type2diabetes	University of Erlangen-Nürnberg Medical School\|Bayer	January 18 2024	Phase 3
NCT06036914	Enrolling by invitation	Heart Failure; With Decompensation	Mayo Clinic	November 27 2023	Phase 2
NCT05536804	Recruiting	Overweight\|Obesity\|Chronic Kidney Disease\|Type 2 Diabetes\|T2D	Eli Lilly and Company	February 8 2023	Phase 2

References

[1] Gunnar Nordin, et al. Clin Chem Lab Med. 2019 Jun 26;57(7):1006-1011.

Chemical Information & Solubility

Molecular Weight	821.14	Formula	C₁₉H₂₆I₃N₃O₉
CAS No.	66108-95-0	SDF	--
Smiles	CC(=O)N(CC(O)CO)C1=C(I)C(=C(I)C(=C1I)C(=O)NCC(O)CO)C(=O)NCC(O)CO
Storage (From the date of receipt)	3 years-21°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-21°C powder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 100 mg/mL ( (121.78 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 100 mg/mL

Ethanol : 100 mg/mL

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

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Molarity Calculator

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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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