Inosine 5′-triphosphate trisodium salt

Name: Inosine 5′-triphosphate trisodium salt
Brand: Selleck Chemicals
SKU: S6103
Rating: 5 (1 reviews)

Catalog No.S6103 Purity:99.82%

Inosine 5′-triphosphate (ITP) is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes.

Inosine 5′-triphosphate trisodium salt Chemical Structure

CAS No. 35908-31-7

Purity & Quality Control

Batch: S610301 Water]100 mg/mL]false]DMSO]Insoluble]false]]]false Purity: 99.82%

99.82

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Biological Activity

Description	Inosine 5′-triphosphate (ITP) is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT06291415	Recruiting	Immune Thrombocytopenia\|Blood Platelet Disorder\|Hematologic Diseases\|Purpura Thrombocytopenic\|Purpura\|Blood Coagulation Disorder\|Thrombotic Microangiopathies\|Hemorrhagic Disorders\|Autoimmune Diseases\|Immune System Diseases\|Hemorrhage\|Pathologic Processes\|Skin Manifestations\|Thrombocytopenia\|Purpura Thrombocytopenic Idiopathic\|Primary Immune Thrombocytopenia\|ITP - Immune Thrombocytopenia	Hutchmed	April 2 2024	Phase 1
NCT06287567	Not yet recruiting	Idiopathic Thrombocytopenic Purpura\|Immune Thrombocytopenia	Institute of Hematology & Blood Diseases Hospital China	March 20 2024	Phase 4
NCT06281327	Recruiting	Immune Thrombocytopenia\|Treatment	Institute of Hematology & Blood Diseases Hospital China\|Henan Cancer Hospital\|Tianjin Medical University Second Hospital\|Tianjin Children''s Hospital\|The Second Affiliated Hospital of Kunming Medical University	March 2024	Phase 2
NCT06094881	Recruiting	Immune Thrombocytopenia\|Treatment	Institute of Hematology & Blood Diseases Hospital China	December 2023	Phase 2
NCT06168851	Recruiting	Immune Thrombocytopenia\|Treatment	Institute of Hematology & Blood Diseases Hospital China	December 28 2023	Phase 2
NCT06107582	Recruiting	Primary Immune Thrombocytopenia	Institute of Hematology & Blood Diseases Hospital China\|Beijing Children''s Hospital\|Tianjin People''s Hospital\|Henan Cancer Hospital\|Tianjin Medical University Second Hospital\|The First Affiliated Hospital of Xiamen University\|The Second Affiliated Hospital of Kunming Medical University	November 1 2023	--

Chemical Information & Solubility

Molecular Weight	574.11	Formula	C₁₀H₁₂N₄Na₃O₁₄P₃
CAS No.	35908-31-7	SDF	--
Smiles	C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+].[Na+]
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

Water : 100 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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