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Imidacloprid-urea

Imidacloprid-urea with a role as a marine xenobiotic metabolite, is the primary imidacloprid soil metabolite, whereas imidacloprid-olefin is the main plant-relevant metabolite and is more toxic to insects than imidacloprid.

Imidacloprid-urea Chemical Structure

Imidacloprid-urea Chemical Structure

CAS No. 120868-66-8

Purity & Quality Control

Batch: S444801 DMSO]42 mg/mL]false]Ethanol]21 mg/mL]false]Water]5 mg/mL]false Purity: 98.95%
98.95

Imidacloprid-urea Related Products

Biological Activity

Description Imidacloprid-urea with a role as a marine xenobiotic metabolite, is the primary imidacloprid soil metabolite, whereas imidacloprid-olefin is the main plant-relevant metabolite and is more toxic to insects than imidacloprid.
In vitro
In vitro

Imidacloprid urea is a metabolite of imidacloprid. Imidacloprid is an effective and widely used neonicotinoid pesticide to control pests of cereals, vegetables, tea and cotton. Imidacloprid can reduce insulin stimulated glucose uptake in adipocytes (3T3-L1), hepatocytes (HepG2), and myotubes (C2C12) cell culture models. Treatment with imidacloprid inhibits phosphorylation of protein kinase B (AKT) and ribosomal S6 kinase (S6K).[2]
Cell Research Cell lines 3T3-L1, HepG2, C2C12
Concentrations 0 μM, 10 μM, 20 μM
Incubation Time 4-6 days
Method

3T3-L1, HepG2, and C2C12 are treated with imidacloprid (0, 10, and 20 μM) for 4-6 days followed by treatment with insulin for 15 min to determine responses. Insulin stimulated glucose uptake and the expressions of p-AKT and p-S6K are determined in all three cells.
In Vivo
In vivo

The brain, liver and kidney of rats exposed with high dose of imidacloprid(20mg/kg/day) show mild pathological changes. [3]
Animal Research Animal Models Female rats (Rattus norvigicus Wistar strain)
Dosages 5 mg/kg, 10 mg/kg, 20 mg/kg
Administration o.g.

Chemical Information & Solubility

Molecular Weight 211.65 Formula

C9H10ClN3O
CAS No. 120868-66-8 SDF --
Smiles ClC1=CC=C(CN2CCNC2=O)C=N1
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 42 mg/mL ( (198.44 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 21 mg/mL

Water : 5 mg/mL


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In vivo
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