Dimethyl pimelimidate dihydrochloride

Name: Dimethyl pimelimidate dihydrochloride
Brand: Selleck Chemicals
SKU: E2999
Rating: 5 (1 reviews)

Synonyms: DMP

Catalog No.E2999 Purity:99.00%

Dimethyl pimelimidate dihydrochloride (DMP) is a homobifunctional amine-reactive crosslinker which is readily hydrolyzed at neutral pH.

Dimethyl pimelimidate dihydrochloride Chemical Structure

CAS No. 58537-94-3

Purity & Quality Control

Batch: E299901 DMSO]45 mg/mL]false]Water]45 mg/mL]false]Ethanol]45 mg/mL]false Purity: 99.00%

99.00

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Related Compound Libraries	FDA-approved Drug Library Natural Product Library Bioactive Compound Library-I Bioactive Compound Library-Ⅱ Express-Pick Library	Click to Expand

Biological Activity

Description	Dimethyl pimelimidate dihydrochloride (DMP) is a homobifunctional amine-reactive crosslinker which is readily hydrolyzed at neutral pH.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT05622643	Recruiting	Multiple Sclerosis	EDMUS Foundation	January 19 2023	--
NCT04600726	Unknown status	Older Adults With Mild Neurocognitive Disorders\|Older Adults With Non-communicable Diseases\|Healthy Age-matched Older Adults	The Hong Kong Polytechnic University\|Department of Neuroscience Psychology and Behavior. The University of Leicester\|School of Psychology The University of Nottingham\|The Alice Ho Miu Ning Nethersole Hospital	February 1 2021	--
NCT04098575	Completed	Diabetes Mellitus Type 2	Boehringer Ingelheim	September 16 2019	--
NCT02809417	Completed	Polypathology	Centre Hospitalier Universitaire de Nice	January 28 2016	--

References

[1] Accoceberry I, et al. J Clin Microbiol. 2001 May;39(5):1947-51.

Chemical Information & Solubility

Molecular Weight	259.17	Formula	C₉H₁₈N₂O₂.2ClH
CAS No.	58537-94-3	SDF	Download Dimethyl pimelimidate dihydrochloride SDF
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 45 mg/mL ( (173.63 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 45 mg/mL

Ethanol : 45 mg/mL

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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