Citicoline

Name: Citicoline
Brand: Selleck Chemicals
SKU: S5362
Rating: 5 (1 reviews)

Synonyms: CDP-choline, cytidine 5'-diphosphocholine

Catalog No.S5362 Purity:99.96%

Citicoline (CDP-choline, cytidine 5'-diphosphocholine) is a naturally occurring compound that acts as nutrient with a broad spectrum of benefits for conditions associated with symptoms of neurological dysfunction. As an endogenous compound, it is also an essential intermediate in the synthesis of cell membrane phospholipids and its formation is the rate-limiting step in phosphatidylcholine synthesis.

Citicoline Chemical Structure

CAS No. 987-78-0

Purity & Quality Control

Batch: S536201 Water]97 mg/mL]false]DMSO]Insoluble]false]]]false Purity: 99.96%

99.96

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Biological Activity

Description

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT05881135	Recruiting	COVID-19	Ohio State University	June 6 2023	Phase 1\|Phase 2
NCT05200208	Recruiting	Alzheimer Disease	Emory University\|National Institute on Aging (NIA)\|Goizueta Alzheimer''s Disease Research Center (ADRC)	July 27 2022	Not Applicable
NCT05315206	Recruiting	Primary Open Angle Glaucoma	Fondazione G.B. Bietti IRCCS	January 25 2022	Not Applicable
NCT05000190	Completed	Attention	PepsiCo Global R&D	September 13 2021	Not Applicable
NCT05154903	Unknown status	Acute Ischemic Stroke	Ain Shams University\|Kafrelsheikh University	July 22 2021	Phase 3
NCT04003090	Completed	Neurodegenerative Diseases	Istituto di Ricerca Neuroftalmologia S.r.l.\|Fondazione G.B. Bietti IRCCS	March 21 2018	Not Applicable

Chemical Information & Solubility

Molecular Weight	488.32	Formula	C₁₄H₂₆N₄O₁₁P₂
CAS No.	987-78-0	SDF	--
Smiles	C[N+](C)(C)CCOP(=O)([O-])OP(=O)(O)OCC1C(C(C(O1)N2C=CC(=NC2=O)N)O)O
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

Water : 97 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

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Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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