ALKBH5 inhibitor 2 (Cpd 20m)

Name: ALKBH5 inhibitor 2 (Cpd 20m)
Brand: Selleck Chemicals
SKU: E1638
Rating: 5 (1 reviews)

Catalog No.E1638 Purity:98.94%

ALKBH5 inhibitor (Cpd 20m) is a potent and selective inhibitor of RNA m6A demethylase AlkB homolog 5 ALKBH5 with IC50 of 21 nM.

ALKBH5 inhibitor 2 (Cpd 20m) Chemical Structure

CAS No. 1505579-77-0

Purity & Quality Control

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Biological Activity

Description	ALKBH5 inhibitor (Cpd 20m) is a potent and selective inhibitor of RNA m6A demethylase AlkB homolog 5 ALKBH5 with IC50 of 21 nM.

References

[1] Fang Z, et al. Eur J Med Chem. 2022 Aug 5:238:114446.

Chemical Information & Solubility

Molecular Weight	272.18	Formula	C₁₁H₇F₃N₂O₃
CAS No.	1505579-77-0	SDF	Download ALKBH5 inhibitor 2 (Cpd 20m) SDF
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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