12-Hydroxydodecanoic acid

Synonyms: G12

12-Hydroxydodecanoic acid (G12) is an active endogenous metabolite.

12-Hydroxydodecanoic acid Chemical Structure

12-Hydroxydodecanoic acid Chemical Structure

CAS No. 505-95-3

Purity & Quality Control

Batch: S308901 DMSO]43 mg/mL]false]Ethanol]43 mg/mL]false]Water]Insoluble]false Purity: 98.22%
98.22

12-Hydroxydodecanoic acid Related Products

Biological Activity

Description

12-Hydroxydodecanoic acid (G12) is an active endogenous metabolite.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06364696 Recruiting
Solid Tumor
Astellas Pharma Inc
April 16 2024 Phase 1
NCT06166836 Recruiting
Solid Tumor
InxMed (Shanghai) Co. Ltd.|InventisBio Co. Ltd
October 12 2022 Phase 1|Phase 2
NCT05492045 Recruiting
NSCLC
InventisBio Co. Ltd
September 13 2022 Phase 1|Phase 2
NCT05400577 Withdrawn
Non-Small Cell Lung Cancer
Fox Chase Cancer Center
July 13 2022 Phase 2

Chemical Information & Solubility

Molecular Weight 216.32 Formula

C12H24O3

CAS No. 505-95-3 SDF --
Smiles OCCCCCCCCCCCC(O)=O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 43 mg/mL ( (198.77 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 43 mg/mL

Water : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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