12-Hydroxydodecanoic acid

Synonyms: G12

Catalog No.S3089 Purity:98.22%

12-Hydroxydodecanoic acid (G12) is an active endogenous metabolite.

12-Hydroxydodecanoic acid Chemical Structure

CAS No. 505-95-3

Purity & Quality Control

Batch: S308901 DMSO]43 mg/mL]false]Ethanol]43 mg/mL]false]Water]Insoluble]false Purity: 98.22%

98.22

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Biological Activity

Description	12-Hydroxydodecanoic acid (G12) is an active endogenous metabolite.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT06364696	Recruiting	Solid Tumor	Astellas Pharma Inc	April 16 2024	Phase 1
NCT06166836	Recruiting	Solid Tumor	InxMed (Shanghai) Co. Ltd.\|InventisBio Co. Ltd	October 12 2022	Phase 1\|Phase 2
NCT05492045	Recruiting	NSCLC	InventisBio Co. Ltd	September 13 2022	Phase 1\|Phase 2
NCT05400577	Withdrawn	Non-Small Cell Lung Cancer	Fox Chase Cancer Center	July 13 2022	Phase 2

Chemical Information & Solubility

Molecular Weight	216.32	Formula	C₁₂H₂₄O₃
CAS No.	505-95-3	SDF	--
Smiles	OCCCCCCCCCCCC(O)=O
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 43 mg/mL ( (198.77 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 43 mg/mL

Water : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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