Metabolism

Tumor Glycolysis ^[1]

GLUTs Inhibitors

WZB117

BAY-876

STF-31

DRB18

Phloretin

HKII Inhibitors

2-DG

Lonidamine

Bromopyruvic acid

PFKFB3 Inhibitors

PFK15

3PO

PFK158

KAN0438757

PKM2 Inhibitors

PKM2 inhibitor

Shikonin

Alkannin

LDHA Inhibitors

Sodium oxamate

-GNE-140

GSK 2837808A

AZ-33

FX11

MCTs Inhibitors

AZD3965

VB124

Syrosingopine

α-cyano-4-hydroxycinnamic acid

BAY-8002

Lipids Metabolism Reprogramming ^[2]

SCAP/SREBPs Inhibitors

PF 429242

Fatostatin

Cinobufotalin

Betulin

Statins

Simvastatin

Pitavastatin calcium

Lovastatin

SLC25A1 Inhibitor

CTPI-2

ACLY Inhibitors

BMS303141

Bempedoic acid

NDI-091143

ACSS2 Inhibitors

Firsocostat

TOFA

ND646

FASN Inhibitors

Denifanstat

C75

TVB-3166

Orlistat

SCD1 Inhibitors

A939572

MF-438

LXR/ABCA1 Agonists

GW3965 HCl

LXR-623

SR9243

CPT1 Inhibitors

Etomoxir sodium salt

Perhexiline maleate

Glutamine Metabolism ^[3]

GLS1/2 Inhibitors

Telaglenastat

BPTES

GK921

Glutamine Depletion

4-PBA

ASCT2/SLC1A5 Inhibitors

V-9302

GPNA

Glutamine Antagonists

JHU-083

6-Diazo-5-oxo-L-norleucine

JHU395

GDH Inhibitors

EGCG

R162

-Epicatechin gallate

GW5074

Bithionol

Aminotransferase Inhibitor

AOA hemihydrochloride

Mitochondrial Metabolism ^[4]

IDH Inhibitors

Ivosidenib

Enasidenib

AGI-6780

Vorasidenib

Olutasidenib

IDH-305

AGI-5198

AG-120

BAY 1436032

SDH Inhibitors

3-Nitropropionic acid

Ethyl potassium malonate

SOD Mimetics

Mito-TEMPO

EUK 134

Deacetylasperulosidic acid

TET1/2 Inhibitors

Bobcat339 hydrochloride

Disodium -2-Hydroxyglutarate

L-2-Hydroxyglutaric acid disodium

KGDH Inhibitors

Devimistat

4-Methyl-2-oxovaleric acid

PDH Inhibitors

DCA

Devimistat

KPLH1130

OXPHOS Inhibitors

IACS-010759

Oligomycin A

FCCP

CCCP

Lixumistat

Gut Microbial Metabolism ^[5]

Lipids

Lipopolysaccharides

Cholesterol

Sphingosine

SCFAs

Sodium butyrate

L-Lactic acid

2-Methylpentanoic acid

Spinach Extract

3-Methylbutanoic acid

Oxalic acid

Sodium propionate

Bile Acids

Lithocholic acid

Cholic acid

Chenodeoxycholic Acid

Hyodeoxycholic acid

Choline Metabolites

Betaine

Trimethylamine N-oxide dihydrate

N-Methylsarcosine

Dimethylamine hydrochloride

Methylamine hydrochloride

Vitamins

Vitamin K2

Biotin

Folic acid

Thiamine HCl

Riboflavin

Pyridoxine

D-Pantothenate Sodium

Nucleotide Metabolism ^[6]

DHODH Inhibitors

Leflunomide

Teriflunomide

Brequinar

Orludodstat

TS Inhibitors

Pemetrexed disodium

5-FU

Raltitrexed

Folinic acid

Pemetrexed

TAS-102

DHFR Inhibitors

Pemetrexed disodium

Methotrexate

Pralatrexate

Pyrimethamine

IMPDH1/2 Inhibitors

Mycophenolic acid

Mizoribine

Merimepodib

RNR Inhibitors

Hydroxyurea

Gemcitabine

Clofarabine

Triapine

Arginine Metabolism ^[7]

PRMT5 Inhibitors

EPZ015666

Pemrametostat

LLY-283

GSK591

Onametostat

PAD4 Inhibitors

Cl-amidine

GSK484 HCl

BMS-P5

ODC Inhibitor

Eflornithine hydrochloride hydrate

ASS1 Inhibitor

Cisplatin

Arginase Inhibitors

Nor-NOHA acetate

Polymyxin B sulphate

L-Norvaline

BEC HCl

Tryptophan Metabolism ^[7]

IDO/TDO Inhibitors

Epacadostat

Indoximod

Navoximod

Linrodostat

IDO-IN-2

IDO inhibitor 1

PF-06840003

LM10

680C91

AHR Inhibitors

PD98059

CH-223191

SR1

BAY-218

BAY 2416964

GNF351

GCN2 Inhibitors

GCN2iB

Serine&Glycine Metabolism ^[7]

PHGDH Inhibitor

NCT-503

CBR-5884

SHMT2 Inhibitor

SIS17

Compound Library