Trimethylamine N-oxide dihydrate

Name: Trimethylamine N-oxide dihydrate
Brand: Selleck Chemicals
SKU: S6042
Rating: 5 (1 reviews)

Catalog No.S6042 Purity: 99.24%

Trimethylamine N-oxide dihydrate, a product of the oxidation of trimethylamine, is considered as a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays.

Trimethylamine N-oxide dihydrate Chemical Structure

CAS: 62637-93-8

Purity & Quality Control

Batch: S604201 DMSO] 22 mg/mL] false] ] ] false] ] ] false Purity: 99.24%

99.24

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Biological Activity

Description	Trimethylamine N-oxide dihydrate, a product of the oxidation of trimethylamine, is considered as a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT06377293	Not yet recruiting	End-Stage Kidney Disease	Far Eastern Memorial Hospital	November 2024	Not Applicable
NCT06120400	Not yet recruiting	Cardiovascular Diseases	Penn State University\|American Egg Board	May 2024	Phase 3
NCT06362356	Recruiting	Hypertensive Disorder of Pregnancy	The Cleveland Clinic	March 5 2024	--
NCT06043531	Recruiting	Liver Transplant	Virginia Commonwealth University	January 18 2024	Not Applicable

Chemical Information & Solubility

Molecular Weight	111.14	Formula	C₃H₁₃NO₃
CAS No.	62637-93-8	SDF	--
Smiles	C[N+](C)(C)[O-].O.O
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 22 mg/mL ( (197.94 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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