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Trimethylamine N-oxide dihydrate

Cat.No.S6042

Trimethylamine N-oxide dihydrate, a product of the oxidation of trimethylamine, is considered as a protein stabilizer that may serve to counteract urea, the major osmolyte of sharks, skates and rays.
Trimethylamine N-oxide dihydrate Chemical Structure

Chemical Structure

Molecular Weight: 111.14

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability

Quality Control

Batch: S604201 DMSO]22 mg/mL]false]]]false]]]false Purity: 99.24%
99.24

Chemical Information, Storage & Stability

Molecular Weight 111.14 Formula

C3H13NO3

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 62637-93-8 -- Storage of Stock Solutions

Synonyms N/A Smiles C[N+](C)(C)[O-].O.O

Solubility

In vitro
Batch:

DMSO : 22 mg/mL (197.94 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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%
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06377293 Not yet recruiting
End-Stage Kidney Disease
Far Eastern Memorial Hospital
 November 2024 Not Applicable
NCT06120400 Not yet recruiting
Cardiovascular Diseases
Penn State University|American Egg Board
 May 2024 Phase 3
NCT06362356 Recruiting
Hypertensive Disorder of Pregnancy
The Cleveland Clinic
 March 5 2024 --
NCT06043531 Recruiting
Liver Transplant
Virginia Commonwealth University
 January 18 2024 Not Applicable

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