Choose Your Country or Region

Biotin (Vitamin B7)

Name: Biotin (Vitamin B7)
Brand: Selleck Chemicals
SKU: S3130
Rating: 5 (2 reviews)

Catalog No.S3130 Purity:99.91%

Biotin(Vitamin B7) is a B-vitamin and acts as a necessary coenzyme for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. Biotin is covalently attached to distinct lysine residues in histones, affecting chromatin structure and mediating gene regulation.

Biotin (Vitamin B7) Chemical Structure

CAS No. 58-85-5

Purity & Quality Control

Batch: Purity: 99.91%

99.91

Biotin (Vitamin B7) Related Products

Related Products	CFSE Propidium Iodide D-Luciferin D-Luciferin sodium salt Crystal Violet Hematoxylin DFO Coelenterazine WST-8 Thiazolyl Blue Dihydroethidium Hoechst 33342 JC-1 Rhodamine B DAPI Dihydrochloride Nile Red Ponceau S MKT-077	Click to Expand
Related Compound Libraries	Metabolism Compound Library Anti-cancer Metabolism Compound Library Glutamine Metabolism Compound Library Carbohydrate Metabolism Compound Library Lipid Metabolism Compound Library	Click to Expand

Biological Activity

Description	Biotin(Vitamin B7) is a B-vitamin and acts as a necessary coenzyme for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. Biotin is covalently attached to distinct lysine residues in histones, affecting chromatin structure and mediating gene regulation.

In vitro
In vitro	Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids. It plays a role in the citric acid cycle, which is the process by which biochemical energy is generated during aerobic respiration. Biotin is a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis. In addition, biotin is widely used throughout the biotechnology industry to conjugate proteins for biochemical assays.

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT06390241	Not yet recruiting	Breast Cancer	Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori	June 2024	Phase 1
NCT06313398	Recruiting	Sickle Cell Disease\|Thalassemia\|Hemoglobinopathy	National Heart Lung and Blood Institute (NHLBI)\|Children''s National Research Institute\|National Institutes of Health Clinical Center (CC)	May 15 2024	Early Phase 1
NCT06242288	Recruiting	Acne Vulgaris	Mostafa Bahaa\|Tanta University	January 30 2024	Phase 3

References

Chemical Information & Solubility

Molecular Weight	244.31	Formula	C₁₀H₁₆N₂O₃S
CAS No.	58-85-5	SDF	Download Biotin (Vitamin B7) SDF
Smiles	C1C2C(C(S1)CCCCC(=O)O)NC(=O)N2
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

In vitro
Batch:

DMSO : 49 mg/mL ( (200.56 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
=	×	×

Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):