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DFO

Synonyms: 9H-1,8-Diazafluoren-9-one, 1,8-Diazafluoren-9-one

DFO (9H-1,8-Diazafluoren-9-one) is a fluorochrome that is used in the forensic field to enhance latent fingerprints deposited on porous surfaces by reacting with the amino acids present in the papillary exudate.

DFO Chemical Structure

DFO Chemical Structure

CAS No. 54078-29-4

Purity & Quality Control

DFO Related Products

Biological Activity

Description DFO (9H-1,8-Diazafluoren-9-one) is a fluorochrome that is used in the forensic field to enhance latent fingerprints deposited on porous surfaces by reacting with the amino acids present in the papillary exudate.
Targets
amino acids [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06066801 Recruiting
Subjects With Diabetes and DFU With a Suspicion of DFO
Assistance Publique - Hôpitaux de Paris
 March 14 2024 Not Applicable
NCT06204237 Recruiting
Peripheral Arterial Occlusive Disease|Critical Limb Ischemia
Aplagon Oy|TRACER Europe BV
 February 1 2024 Early Phase 1
NCT05974579 Recruiting
Amyotrophic Lateral Sclerosis
Université de Sherbrooke|Eli Lilly and Company|Chorus Wellness Inc.|AL-S Pharma AG
 November 23 2023 Phase 1
NCT05955833 Recruiting
Breast Cancer|Metastatic Breast Cancer|HER2-positive Breast Cancer|Gastric Cancer|Metastatic Gastric Cancer|HER2-positive Gastric Cancer
Amsterdam UMC location VUmc|AstraZeneca
 June 26 2023 Phase 1

Chemical Information & Solubility

Molecular Weight 182.18 Formula

C11H6N2O
CAS No. 54078-29-4 SDF --
Smiles C1=CC2=C(C(=O)C3=C2C=CC=N3)N=C1
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 36 mg/mL ( (197.6 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 2 mg/mL

Ethanol : Insoluble


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In vivo
Batch:

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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