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Technical Data
| Formula | C11H6N2O |
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| Molecular Weight | 182.18 | CAS No. | 54078-29-4 | |
| Solubility (25°C)* | In vitro | DMSO | 36 mg/mL (197.6 mM) | |
| Water | 2 mg/mL (10.97 mM) | |||
| Ethanol | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Preparing Stock Solutions
Biological Activity
| Description | DFO (9H-1,8-Diazafluoren-9-one) is a fluorochrome that is used in the forensic field to enhance latent fingerprints deposited on porous surfaces by reacting with the amino acids present in the papillary exudate. | |
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Protocol (from reference)
Selleck's DFO has been cited by 12 publications
| BSA-stabilized selenium nanoparticles ameliorate intracerebral hemorrhage's-like pathology by inhibiting ferroptosis-mediated neurotoxicology via Nrf2/GPX4 axis activation [ Redox Biol, 2024, 75:103268] | PubMed: 39032396 |
| TRIB3 promotes malignancy of head and neck squamous cell carcinoma via inhibiting ferroptosis [ Cell Death Dis, 2024, 15(3):178] | PubMed: 38429254 |
| Selective PI3Kδ inhibitor TYM-3-98 suppresses AKT/mTOR/SREBP1-mediated lipogenesis and promotes ferroptosis in KRAS-mutant colorectal cancer [ Cell Death Dis, 2024, 15(7):474] | PubMed: 38956060 |
| Deferoxamine topical cream superior to patch in rescuing radiation-induced fibrosis of unwounded and wounded skin [ J Cell Mol Med, 2024, 28(8):e18306] | PubMed: 38613357 |
| Pivotal Role of GSTO2 in Ferroptotic Neuronal Injury After Intracerebral Hemorrhage [ J Mol Neurosci, 2024, 74(1):24] | PubMed: 38386166 |
| Overburdened ferroptotic stress impairs tooth morphogenesis [ Elife, 2023, 12RP88745] | PubMed: 37991825 |
| NF-κB Inhibitor Myrislignan Induces Ferroptosis of Glioblastoma Cells via Regulating Epithelial-Mesenchymal Transformation in a Slug-Dependent Manner [ Oxid Med Cell Longev, 2023, 2023:7098313] | PubMed: 36699318 |
| Curcumin Analog, HO-3867, Induces Both Apoptosis and Ferroptosis via Multiple Mechanisms in NSCLC Cells with Wild-Type p53 [ Evid Based Complement Alternat Med, 2023, 2023:8378581] | PubMed: 36814470 |
| Phospholipid peroxidation-driven modification of chondrogenic transcription factor mediates alkoxyl radicals-induced impairment of embryonic bone development [ Redox Biol, 2022, 56:102437] | PubMed: 36037588 |
| mRNA-Modified FUS/NRF2 Signalling Inhibits Ferroptosis and Promotes Prostate Cancer Growth [ Comput Math Methods Med, 2022, 2022:8509626] | PubMed: 36035281 |
RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.