DFO

Catalog No.S6849 Batch:S684901

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Technical Data

Formula

C11H6N2O

Molecular Weight 182.18 CAS No. 54078-29-4
Solubility (25°C)* In vitro DMSO 36 mg/mL (197.6 mM)
Water 2 mg/mL (10.97 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
* Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.)

Preparing Stock Solutions

Biological Activity

Description DFO (9H-1,8-Diazafluoren-9-one) is a fluorochrome that is used in the forensic field to enhance latent fingerprints deposited on porous surfaces by reacting with the amino acids present in the papillary exudate.
Targets
amino acids [1]

Protocol (from reference)

Selleck's DFO has been cited by 11 publications

BSA-stabilized selenium nanoparticles ameliorate intracerebral hemorrhage's-like pathology by inhibiting ferroptosis-mediated neurotoxicology via Nrf2/GPX4 axis activation [ Redox Biol, 2024, 75:103268] PubMed: 39032396
TRIB3 promotes malignancy of head and neck squamous cell carcinoma via inhibiting ferroptosis [ Cell Death Dis, 2024, 15(3):178] PubMed: 38429254
Selective PI3Kδ inhibitor TYM-3-98 suppresses AKT/mTOR/SREBP1-mediated lipogenesis and promotes ferroptosis in KRAS-mutant colorectal cancer [ Cell Death Dis, 2024, 15(7):474] PubMed: 38956060
Deferoxamine topical cream superior to patch in rescuing radiation-induced fibrosis of unwounded and wounded skin [ J Cell Mol Med, 2024, 28(8):e18306] PubMed: 38613357
Pivotal Role of GSTO2 in Ferroptotic Neuronal Injury After Intracerebral Hemorrhage [ J Mol Neurosci, 2024, 74(1):24] PubMed: 38386166
Overburdened ferroptotic stress impairs tooth morphogenesis [ Elife, 2023, 12RP88745] PubMed: 37991825
NF-κB Inhibitor Myrislignan Induces Ferroptosis of Glioblastoma Cells via Regulating Epithelial-Mesenchymal Transformation in a Slug-Dependent Manner [ Oxid Med Cell Longev, 2023, 2023:7098313] PubMed: 36699318
Curcumin Analog, HO-3867, Induces Both Apoptosis and Ferroptosis via Multiple Mechanisms in NSCLC Cells with Wild-Type p53 [ Evid Based Complement Alternat Med, 2023, 2023:8378581] PubMed: 36814470
Phospholipid peroxidation-driven modification of chondrogenic transcription factor mediates alkoxyl radicals-induced impairment of embryonic bone development [ Redox Biol, 2022, 56:102437] PubMed: 36037588
Sphingosine-1-phosphate transporter spinster homolog 2 is essential for iron-regulated metastasis of hepatocellular carcinoma [ Mol Ther, 2021, S1525-0016(21)00467-6] PubMed: 34547466

RETURN POLICY
Selleck Chemical’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.

SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.

NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.