Home Microbiology Antineoplastic and Immunosuppressive Antibiotics inhibitor - Antibiotics chemical - Antibiotics for Mammalian Cell Culture chemical Polymyxin B sulphate For research use only.

Polymyxin B sulphate

Synonyms: Aerosporin, PMB, Poly-RX

Polymyxin B (Aerosporin, PMB, Poly-RX) is an antibiotic primarily used for resistant gram-negative infections.

Polymyxin B sulphate Chemical Structure

Polymyxin B sulphate Chemical Structure

CAS No. 1405-20-5

Purity & Quality Control

Polymyxin B sulphate Related Products

Biological Activity

Description Polymyxin B (Aerosporin, PMB, Poly-RX) is an antibiotic primarily used for resistant gram-negative infections.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06386003 Not yet recruiting
Post Traumatic Stress Disorder|PTSD|Chronic PTSD
Unity Health Toronto|Toronto Metropolitan University|University of Ottawa
 August 2024 Phase 2
NCT06407635 Not yet recruiting
Post Traumatic Stress Disorder
Johns Hopkins University
 May 2024 Phase 1
NCT05732779 Not yet recruiting
Heart Transplant Rejection|Immune Suppression|Pediatric Heart Transplant|Medication Nonadherence|Health Behavior|Remote Monitoring|Patient Engagement
University of Florida|emocha Mobile Health Inc.|National Heart Lung and Blood Institute (NHLBI)
 March 31 2024 Not Applicable
NCT01795872 Completed
Multiple Sclerosis
Bayer
 September 2013 Phase 4

Chemical Information & Solubility

Molecular Weight 1301.56 Formula

C56H98N16O13.H2SO4
CAS No. 1405-20-5 SDF Download Polymyxin B sulphate SDF
Smiles CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CCN)CC2=CC=CC=C2)CC(C)C)CCN)CCN)C(C)O.OS(=O)(=O)O
Storage (From the date of receipt)

In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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