Anti-infection

Anti-infection Products

  • All (150)
  • Anti-infection Inhibitors (31)
  • Anti-infection Antagonist (1)
  • Anti-infection Modulators (3)
  • New Anti-infection Products
Catalog No. Product Name Information Product Use Citations Product Validations
S5001 Tofacitinib (CP-690550) Citrate Tofacitinib citrate (CP-690550, Tasocitinib) is a novel inhibitor of JAK with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively. Tofacitinib citrate has anti-infection activity.
J Exp Clin Cancer Res, 2024, 43(1):64
Antimicrob Agents Chemother, 2024, 68(4):e0135023.
Front Oncol, 2024, 14:1386190
S4157 Chloroquine diphosphate Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. Chloroquine is also an inhibitor of toll-like receptors (TLRs).
Nat Commun, 2024, 15(1):1642
Cancer Lett, 2024, 604:217258
Phytomedicine, 2024, 135:156053
S4430 Hydroxychloroquine (HCQ) Sulfate Hydroxychloroquine (HCQ) Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.
Redox Biol, 2024, 75:103274
Phytomedicine, 2024, 10.1016/j.phymed.2023.155152
Breast Cancer Res, 2024, 26(1):33
S8279 Shikonin Shikonin, a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay. Shikonin exerts an anti-inflammatory effect by inhibiting tumor necrosis factor-α (TNF-α) and prevents activation of nuclear factor-κB (NF-κB) pathway via proteasome inhibition.
Elife, 2024, 12RP91141
Elife, 2024, 12RP91141
Mol Ther Methods Clin Dev, 2024, 32(3):101307
S4592 SBE-β-CD SBE-β-CD is a novel, chemically modified cyclodextrin with a structure designed to optimize the solubility and stability of drugs.
Nat Commun, 2024, 15(1):5703
Cell Death Differ, 2024, 31(10):1318-1332
Cell Death Differ, 2024, 10.1038/s41418-024-01316-3
S8068 Chaetocin Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively. Chaetocin is an anticancer agent and inhibitor of thioredoxin reductase (TrxR).
Int J Mol Sci, 2024, 25(17)9215
PeerJ, 2024, 12:e17222
Asian Pac J Trop Bio, 2023;, 13(6): 268-276
S2264 Artemether Artemether (SM-224, CGP 56696) is an antimalarial for the treatment of resistant strains of falciparum malaria.
J Pers Med, 2022, 12(2)258
Hum Cell, 2022, 10.1007/s13577-022-00671-y
Sci Rep, 2021, 11(1):14571
S2572 Streptomycin sulfate Streptomycin sulfate(Phytomycin) is a sulfate salt of streptomycin that is a protein synthesis inhibitor.
Front. Oncol, 2023-, Volume 13
Front Oncol, 2023, 13:1118268
Transl Oncol, 2022, 26:101502
S7465 FTI 277 HCl FTI 277 HCl is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. FTI 277 HCl inhibits cell growth and induces apoptosis. FTI 277 HCl is effective in clearing HDV viremia.
Cancer Res, 2023, 83(13):2248-2261
PLoS Biol, 2021, 19(4):e3001134
Cell Struct Funct, 2021, 46(1):1-9
S2479 Lincomycin HCl Lincomycin hydrochloride (Lincocin, NSC 70731,U10149A) is the monohydrated salt of lincomycin, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis.
J Pers Med, 2022, 12(2)258
Hum Cell, 2022, 10.1007/s13577-022-00671-y
Hum Cell, 2021, 10.1007/s13577-021-00639-4
S2613 Clorsulon Clorsulon (MK-401,L631529) is used in the treatment of Fasciola hepatica infections in calves and sheep.
J Pers Med, 2022, 12(2)258
Hum Cell, 2022, 10.1007/s13577-022-00671-y
Hum Cell, 2021, 34(6):1911-1918
S1282 Artemisinin Artemisinin is a sesquiterpene endoperoxide which is a potent antimalarial agent.
Virus Res, 2024, 349:199448
Drug Des Devel Ther, 2023, 17:1679-1697
Cancer Cell, 2022, S1535-6108(22)00312-9
S4147 Azithromycin Dihydrate Azithromycin Dihydrate(CP-62993 dihydrate) is an acid stable orally administered macrolide antimicrobial drug, structurally related to erythromycin.
J Cell Biochem, 2022, 10.1002/jcb.30213
Adv Ther (Weinh), 2020, 2000034
PLoS Comput Biol, 2020, 16(12):e1008489
S4420 Mefloquine HCl Mefloquine HCl(Mefloquin hydrochloride) is a blood schizonticide by inhibiting hemozoin formation, used as an antimalarial drug.
Mol Med Rep, 2021, 23(1)40
bioRxiv, 2020, 2020/9/20.4.7.30734
Int J Parasitol Drugs Drug Resist, 2018, 8(2):331-340
S3649 Ceftazidime Ceftazidime(GR20263) is a third-generation cephalosporin that has activity against Gram-negative bacilli, including Pseudomonas aeruginosa.
Mol Cancer, 2024, 23(1):242
Pharmacol Res, 2024, 201:107096
ACS Infect Dis, 2023, 10.1021/acsinfecdis.3c00264
S7896 Sodium Tauroursodeoxycholate (TUDC) Sodium Tauroursodeoxycholate (TUDC) is a water soluble bile salt, used for the treatment of gallstones and liver cirrhosis.
iScience, 2024, 27(8):110598
Infect Immun, 2024, 92(8):e0030024
Microbiome, 2019, 7(1):145
S4237 Primaquine Diphosphate Primaquine Diphosphate is a transmission-blocking anti-malarial clinically available, displaying a marked activity against gametocytes of all species of human malaria.
J Extracell Vesicles, 2024, 13(7):e12494
Front Pharmacol, 2021, 12:695009
Cell Syst, 2019, 8(2):97-108
S3941 Pinocembrin Pinocembrin (Dihydrochrysin, Galangin flavanone, 5,7-Dihydroxyflavanone) is a major flavonoid molecule incorporated as multifunctional in the pharmaceutical industry. Its vast range of pharmacological activities has been well researched including antimicrobial, anti-inflammatory, antioxidant, and anticancer activities.
Neurol Res, 2022, 1-10
J Neuroinflammation, 2020, 17(1):337
S5184 Dexamethasone palmitate Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone (DXM), is a glucocorticoid receptor agonist with a 47-fold lower affinity for the glucocorticoid receptor than DXM. Dexamethasone palmitate (DXP) exhibits anti-inflammatory activity.
Dis Model Mech, 2022, dmm.049109
Hematology, 2022, 27(1):32-42
S1553 Delafloxacin (ABT-492) Delafloxacin (ABT-492, RX-3341, WQ-3034) is a new fluoroquinolone against 155 aerobic and 171 anaerobic pathogens.
Molecules, 2023, 28(6)2820
Molecules, 2023, 28(6), 2820
S5397 Chlorhexidine Chlorhexidine is a disinfectant and topical anti-infective agent that is active against Gram-positive and Gram-negative organisms, facultative anaerobes, aerobes, and yeasts.
J Cell Mol Med, 2021, 10.1111/jcmm.16673
BMC Microbiol, 2020, 20(1):275
S2282 Cinchonidine Cinchonidine is an alkaloid used in asymmetric synthesis in organic chemistry.
CNS Neurosci Ther, 2023, 10.1111/cns.14403
J Med Virol, 2019, 91(8):1440-1447
S5967 Berberine chloride hydrate Berberine (Natural Yellow 18) chloride hydrate is a quaternary ammonium salt from the group of isoquinoline alkaloids. Berberine activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. Berberine chloride decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. Berberine chloride induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. Berberine chloride is a dual topoisomerase I and II inhibitor. Berberine chloride is also a potential autophagy modulator.
Front Biosci (Landmark Ed), 2022, 27(8):242
Front Pharmacol, 2021, 12:632201
S4192 Chlorquinaldol Chlorquinaldol(Chloquinan) is an antimicrobial agent used for local antisepsy.
Biosensors (Basel), 2023, 13(6)571
Biosensors (Basel), 2023, 13(6)571
ACS Synth Biol, 2022, 11(8):2820-2828
S5961 Prednisolone disodium phosphate Prednisolone disodium phosphate (Hydeltrasol, Prednisolone 21-phosphate disodium) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties that exerts late mitogenic and biphasic effects on resistant acute lymphoblastic leukemia cells.
J Immunotoxicol, 2021, 18(1):154-162
Eur J Rheumatol, 2021, 10.5152/eurjrheum.2021.20054
S4759 p-Coumaric Acid p-Coumaric acid (4-Hydroxycinnamic acid, P-Hydroxycinnamic acid, 4-Coumaric acid, Trans-p-Coumaric acid, para-Coumaric Acid) is a hydroxy derivative of cinnamic acid found in a variety of edible plants and is reported to have antioxidant, anti-inflammatory, and antimicrobial activity.
Exp Ther Med, 2021, 21(5):503
J Nutr Biochem, 2015, 26(11):1379-84
S7411 Ascomycin (FK520) Ascomycin (FK520, FR 900520, Immunomycin), an FK-506 analog, is a neutral macrolide immunosuppressant, which prevents rejection after an organ transplant. Phase 3.
ACS Nano, 2024, 18(45):31451-31465
Melanoma Res, 2020, 30(4):325-335
Virol Sin, 2019, 34(6):648-661
S5927 Proguanil Proguanil (chlorguanide, chloroguanide) is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.
Int J Med Sci, 2022, 19(2):233-241
Sci Adv, 2021, 7(27)eabh3032
P1201 LL37 (Human cathelicidin) LL37 (Human cathelicidin, Ropocamptide) is a cathelicidin-related antimicrobial peptide with potent chemotactic and immunomodulatory properties.
Biomed Pharmacother, 2023, 157:114091
Biomed Pharmacother, 2022, 153:113292
S3746 Lumefantrine Lumefantrine (benflumetol) is an antimalarial agent used to treat acute uncomplicated malaria.
Antimicrob Agents Chemother, 2021, AAC.02137-20
ACS Infect Dis, 2020, 10.1021/acsinfecdis.0c00522
S9131 Punicalagin Punicalagin, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects., Punicalagin, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects.
SLAS Discov, 2024, S2472-5552(24)00007-8
Cell, 2020, 30;181(3):637-652.e15.
Cell, 2020, 30;181(3):637-652e15
S4242 Cetrimonium Bromide (CTAB) Cetrimonium Bromide (CTAB) is a known component of the broad-spectrum antiseptic cetrimide, which is a mixture of different quaternary ammonium salts.
Biochem Cell Biol, 2021, 10.1139/bcb-2020-0570
Micromachines (Basel), 2018, 9(6)
S9185 Nitidine Chloride Nitidine Chloride, a benzophenanthridine alkaloid found in species of the genus Zanthoxylum, has an anti-malarial activity.
Int Immunopharmacol, 2021, 101(Pt A):108273
Front Cell Neurosci, 2020, 14:216
S3067 Chlorhexidine 2HCl Chlorhexidine hydrochloride (NSC-185) is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms.
BMC Microbiol, 2020, 20(1):275
S2537 Secnidazole Secnidazole (Flagentyl, PM 185184, RP 14539) is a nitroimidazole anti-infective.
Microorganisms, 2022, 10(7)1421
S4195 Broxyquinoline Broxyquinoline(Dibromohydroxyquinoline) is an antiprotozoal agent and able to release oxygen free radicals from the water in mucous membranes.
ACS Synth Biol, 2022, 11(8):2820-2828
S4196 Ethacridine lactate monohydrate Ethacridine lactate monohydrate(Acrinol monohydrat) is an aromatic organic compound based on acridine used as an antiseptic agent.
Carcinogenesis, 2014, 35(12):2822-30
S4726 Lauric Acid Lauric Acid (dodecanoic acid, N-Dodecanoic acid, Dodecylic acid) is a saturated medium-chain fatty acid with a 12-carbon backbone. Lauric acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.
Nat Commun, 2023, 14(1):660
S6288 Chlorhexidine diacetate Chlorhexidine diacetate (Hibitane diacetate) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.
BMC Microbiol, 2020, 20(1):275
S4041 Olsalazine Sodium Olsalazine Sodium is an anti-inflammatory prodrug, which consists of two 5-ASA moieties linked by an azo bond.
Oncotarget, 2017, 8(1):228-237
S6185 Arachidonic acid Arachidonic acid (Arachidonate) is an unsaturated, essential fatty acid found in animal and human fat as well as in the liver, brain, and glandular organs. It is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.,
Bone Res, 2022, 10(1):20
S4172 Cetylpyridinium Chloride Cetylpyridinium chloride(CPC) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.
iScience, 2024, 27(8):110598
Int J Mol Sci, 2023, 24(11)9708
S2395 Rheochrysidin Rheochrysidin (Physcione) is an anthraquinone from roots of Rheum officinale Baill.
ACS Chem Biol, 2015, 10.1021/cb5009487
S4081 Sulfacetamide Sodium Sulfacetamide Sodium is an anti-biotic.
G3 (Bethesda), 2020, 4;10(5):1585-1597
S9387 Maackiain Maackiain (Demethylpterocarpin) is a pterocarpan that is widely distributed in leguminous plants. It has anticancer and antimicrobial effects.
Int Immunopharmacol, 2022, 108:108710
S5096 SulfadiMethoxine sodium Sulfadimethoxine (Sulfadimethoxydiazine) is a long-lasting sulfonamide antimicrobial agent used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections.
Cell Death Dis, 2018, 9(6):646
E0206 Ginkgetin

Ginkgetin is a biflavone from Ginkgo biloba leaves with anti-cancer, anti-inflammatory, anti-microbial, anti-adipogenic, and neuroprotective activities.

Biomed Pharmacother, 2022, 154:113628
S5214 Imidocarb dipropionate Imidocarb is an antiprotozoal agent, used as dipropionate in the treatment of babesiosis and ehrlichiosis.
Nat Commun, 2017, 8(1):823
S7867 Oleuropein Oleuropein is an antioxidant polyphenol isolated from olive leaf. Oleuropein exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. Oleuropein inhibits PPARγ activity. Oleuropein exerts anti-adipogenic effect through direct inhibition of PPARγ transcriptional activity. Oleuropein also inhibits aromatase. Oleuropein induces apoptosis. Phase 2.
Front Endocrinol (Lausanne), 2024, 15:1354435
J Med Virol, 2019, 91(8):1440-1447
S3220 Trigonelline Trigonelline (Trigenolline) is a plant alkaloid and a major component of coffee and fenugreek with anti-degranulation, anti-diabetic, antioxidant, anti-inflammatory, and neuroprotective effects. Trigonelline inhibits FcεRI-mediated intracellular signaling pathways, such as phosphorylation of PLCγ1, PI3K, and Akt. Trigonelline (Trigenolline) also inhibits the microtubule formation in RBL-2H3 cells.
Biomed Pharmacother, 2021, 143:112204
S3279 Polyphyllin B (Formosanin C) Polyphyllin B (Formosanin C, FC), a diosgenin saponin isolated from Paris formosana, is an immunomodulator with antitumor activity. Polyphyllin B (Formosanin C, FC) induces apoptosis.
Oncol Lett, 2021, 22(1):550
S1644 Nitrofural Nitrofural (Nitrofurazone) is a topical anti-infective agent with an IC50 of 22.83 ± 1.2 μM. (Rat LD50 = 590 mg/kg)
S2469 Fleroxacin Fleroxacin (Ro 23-6240,AM-833,Quinodis, Megalocin) is a new broad-spectrum fluoroquinolone.
S3116 Sulfathiazole Sulfathiazole is an organosulfur compound that has been used as a short-acting sulfa drug.
S2511 Sulfadoxine Sulfadoxine (Sulphadoxine) is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax.
S4191 Betamipron Betamipron (CS-443,N-Benzoyl-β-alanine) is a chemical compound which is used together with panipenem to inhibit panipenem uptake into the renal tubule and prevent nephrotoxicity.
S2612 Ribitol Ribitol (Adonitol) is a crystalline pentose alcohol and is formed by the reduction of ribose which is occurs naturally in the plant Adonis vernalis.
E0524 Spinosad Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete, is a biological neurotoxic insecticide with a broader action spectrum, targeting the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system.
E0525 Colistin Colistin(Polymyxin E), a cyclic polypeptide antibiotic synthesized by Bacillus polymyxa subspecies colistinus Koyama, exerts antimicrobial activity by targeting at the bacterial cell membrane.
S3226 Dehydroabietic acid Dehydroabietic acid (DAA, DHAA), a naturally occurring diterpene resin acid derived from coniferous plants such as Pinus and Picea, displays anti-inflammatory activity via suppression of Src-, Syk-, and TAK1-mediated pathways.
S4945 Ethacridine lactate Ethacridine lactate (Acrinol) is an aromatic organic compound based on acridine used as an antiseptic agent. Ethacridine lactate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.
S9564 p-Hydroxy-cinnamic Acid p-Hydroxy-cinnamic Acid has in vitro antimalarial activity and in vivo anti-osteoporotic properties.
E4872New Mefloquine Mefloquine(Lariam, WR-142490) is a quinoline antimalarial drug and an antagonist of K+ channel (KvQT1/minK) with an IC50 of ~1 μM. It is widely used in both the treatment and prophylaxis of Plasmodium falciparum malaria, and can prolong cardiac repolarization.
S9094 Pogostone Pogostone is one of the secondary metabolites from Pogostemon cablin (Blanco) Benth. (Lamiaceae), serving as the effective component of the antimicrobial activity.
J Ethnopharmacol, 2021, 278:114250
S3269 Acetylcorynoline Acetylcorynoline, a major alkaloid component derived from Corydalis bungeana which is a traditional Chinese medical herb, shows anti-inflammatory properties. Acetylcorynoline may decrease egl-1 expression to suppress apoptosis pathways and increase rpn5 expression to enhance the activity of proteasomes.
S3270 Genipin 1-O-beta-D-gentiobioside Genipin 1-O-beta-D-gentiobioside (GG, Genipin 1-β-D-gentiobioside, Genipin 1-gentiobioside, Genipin 1-β-gentiobioside, Genipin gentiobioside) is a bioactive iridoid glycoside isolated from Gardenia jasminoides Ellis (Zhizi in Chinese) that exhibits hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities.
S3308 Caftaric acid Caftaric acid (CA, Caffeoyl tartaric acid) is a natural product that shows anti-oxidant and anti-inflammatory effects.
E3085 Dichroae Radix Extract Dichroae Radix Extract is drawed from Dichroae radix, exhibits good clinical efficacy in treatments as an antimalarial, expectorant or antifebrile agent in Chinese medicine, and it also has an anticoccidial effect in chickens infected by coccidiosis when used alone or as the main herb to formulate a complex.
E3107 Andrographis Herba Extract Andrographis Herba Extract is obtained from the aerial part of Andrographis paniculata (Burm. F.) Nees, has various activities including antimicrobial and antioxidant, antimalarial, antiangiogenic, anti-inflammatory, anti-diabetic, and in vitro α-glucosidase and α-amylase enzyme inhibitory activities.
S4142 Clopidol Clopidol (WR 61112) is an antiprotozoal agent.
S5700 Phthalylsulfathiazole Phthalylsulfathiazole (Sulfathalidine) is a broad-spectrum antimicrobial that can treat different types of infections including intestinal.
Med Oncol, 2024, 41(8):188
S6136 (±)-α-Bisabolol α-bisabolol is a small, plant-derived, oily sesquiterpene alcohol with some anti-inflammatory and even anti-microbial properties.
S5757 Isoeugenol Isoeugenol (4-Propenylguaiacol), an essential oil constituent of nutmeg, clove, and cinnamon, shows antimicrobial activity.
S0320 Cycloguanil hydrochloride Cycloguanil hydrochloride, an active metabolite of proguanil, acts on malaria schizonts in erythrocytes and hepatocytes.
S4250 Sulfamethoxypyridazine Sulfamethoxypyridazine (CL 13494) is a long-acting sulfonamide for treatment of Dermatitis herpetiformis.
S6173 Amylmetacresol Amylmetacresol is an antiseptic used to treat infections of the mouth and throat.
S4946 2,3-Dihydroxybenzoic acid 2,3-Dihydroxybenzoic acid (Pyrocatechuic acid, 3-Hydroxysalicylic acid, Hypogallic acid) is a natural phenol found in Phyllanthus acidus and in the aquatic fern Salvinia molesta, also a product of human aspirin metabolism. It is a potentially useful iron-chelating drug and has antimicrobial properties.
S2271 Berberine chloride Berberine chloride is a quaternary ammonium salt from the group of isoquinoline alkaloids. Berberine activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. Berberine chloride decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. Berberine chloride induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. Berberine chloride is a dual topoisomerase I and II inhibitor. Berberine chloride is also a potential autophagy modulator.
Adv Healthc Mater, 2023, e2300591.
Transl Oncol, 2023, 35:101712
J Biomol Struct Dyn, 2022, 1-11
S5475 Novaluron Novaluron (Rimon) belongs to the class of insecticides called insect growth regulators with pesticide properties.
S3218 Amiloxate Amiloxate (Amiloxiate, Isoamyl Methoxycinnamate, Isopentyl 4-methoxycinnamate, Isoamyl 4-methoxycinnamate, Isoamyl p-methoxycinnamate, Isopentyl p-methoxycinnamate) is EMA-approved chemical UV-filter used in cosmetics. Amiloxate is a cinnamic acid derivative with anti-inflammatory activity.
S5963 Sulfathiazole sodium Sulfathiazole sodium, an antimicrobial agent, is an organosulfur compound that has been used as a short-acting sulfa drug.
S6243 Ethyl pyruvate Ethyl pyruvate (CTI-01) is a simple aliphatic ester of pyruvic acid and has been shown to have robust neuroprotective effects via its anti-inflammatory, anti-oxidative, and anti-apoptotic functions.
BMC Gastroenterol, 2024, 24(1):245
S3695 Cystamine dihydrochloride Cystamine dihydrochloride (Decarboxycystine, 2-Aminoethyl disulfide, 2,2'-Dithiobisethanamine) acts as an anti-infective agent, which is used in the treatment of urinary tract infections and also as a radiation-protective agent that interferes with sulfhydryl enzymes.
S4175 Sulfaguanidine Sulfaguanidine is a sulfonamide used as an anti-infective agent.
S3787 Picroside I Picroside I (6'-Cinnamoylcatalpol), an iridoid glycoside, is a hepatoprotective agent which is reported to be antimicrobial and used against hepatitis B.
S9016 Dipsacoside B Dipsacoside B, extracted from the flowerbuds of Lonicera confusa DC, shows strong antimicrobial activity.
S5908 Garenoxacin Garenoxacin (T-3811ME, BMS-284756) is a novel des-F(6) quinolone that has been shown to be effective in vitro against a wide range of clinically important pathogens, including gram-positive and gram-negative aerobes and anaerobes.
E3166 Fermented Blank Bean Extract Fermented Blank Bean Extract is extracted from the fermented Phaseolus vulgaris L., and aids in protection of the human digestive tract, mainly the colon.
S4062 Ronidazole Ronidazole is an antiprotozoal agent.
S4971 Buparvaquone Buparvaquone (Butalex) is a second-generation hydroxynaphthoquinone related to parvaquone, with novel features that make it a promising compound for the therapy and prophylaxis of all forms of theileriosis.
S6761 Dalfopristin Dalfopristin (RP54476) is a semi-synthetic analogue of ostreogyrcin A. Quinupristin/dalfopristin (Q/D) is a parental streptogramin with a spectrum of activity that includes Gram-positive pathogens, including those resistant to other classes of antimicrobial compounds.
S5292 Diazolidinyl urea Diazolidinyl urea (Germall II) is an antimicrobial preservative used in cosmetics.
E3350 Goodyera kwangtungensis Tso. extract Goodyera kwangtungensis Tso. Extract is obtained from Goodyera kwangtungensis C.L. Tso, the entire plant is used to improve the condition of the lungs and to clear phlegm.
S3210 3'-Hydroxy-4'-methoxyacetophenone 3'-Hydroxy-4'-methoxyacetophenone (Acetoisovanillone, Isoacetovanillone, Diosmin EP Impurity A) is an active P. spinosa extract with anti-inflammatory potential.
E0626 AX 20017 AX 20017 is a small-molecule protein kinase G (PknG) inhibitor with an IC50 of 0.39 μM.
S5887 Khellin Khellin (Methafrone, Visammin, Ammivisnagen, Khellinorm, Medekellin, Viscardan, Kalangin), a compound isolated from the seeds of Ammi Visnaga Lam (Umbelliferae), is used to treat a variety of maladies.
E0820 OX02983 OX02983 is a novel anthelmintic agent, actives against both egg and adult stages of Trichuris parasites, immobilising whipworm and reducing the ability of embryonated Trichuris muris eggs to establish infection in the mouse host.
S4303 9-Aminoacridine 9-Aminoacridine (Aminacrine) is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator and a negative mode small molecule MALDI matrix.
E6014New Primaquine Primaquine (Primachin), an 8-aminoquinoline, is an antimalarial agent and a potent gametocytocidal in falciparum malaria. It also prevents relapse in vivax and ovale malaria.
S0146 Broxaldine Broxaldine (Brobenzoxaldine, AL307) is an antiprotozoal drug and can be used in leprosy.
S4417 Ceftaroline Fosamil

Ceftaroline fosamil (CX-0903, DSP-5990, PPI-0903, TAK-599, Teflaro, Zinforo) is a cephalosporin with activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA).

S0846 Euquinine Euquinine is generally used as a febrifuge, antimalarial, and tonic.
E2137 WAY-297407 WAY-297407 is a bioactive compound.
E0749 Coumalic acid Coumalic acid is a valuable platform compound which can be prepared from malic acid, can be used in the flavours, fragrances and cosmetics industries, as polymer components, and as pharmaceutical scaffolds displaying anti-bronchial and -malarial activity.
S9084 Rhoifolin Rhoifolin (Rhoifoloside, Apigenin 7-O-neohesperidoside, Apigenin-7-O-rhamnoglucoside), a natural glycoside of apigenin, has been obtained from the green leaves of Rhus succedanea and possesses a variety of significant biological activities including antioxidant, anti-inflammatory, antimicrobial, hepatoprotective and anticancer effects.
E3695 Hypericum japonicum Extract Hypericum Japonicum Extract is obtained from the entire herb of Hypericum japonicum, has been widely used for the treatment of bacterial diseases, infectious hepatitis, acute and chronic hepatitis, gastrointestinal disorder, internal hemorrhage and tumour.
E2665 Tafenoquine Tafenoquine (WR 238605) is an 8-aminoquinoline, used as an anti-malarial prophylactic agent.
S6771 MAC-545496 MAC-545496 is a nanomolar glycopeptide-resistance-associated protein R(GraR) inhibitor with strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM). MAC-545496 can reverse β-lactam resistance in methicillin-resistant strains and synergize with CAMPs. MAC-545496 shows remarkable activity in macrophages and attenuates S. aureus virulence in a G. mellonella larvae infection model.
E2812 Antimalarial agent 1 Antimalarial agent 1 is a potent antimalarial drug.
E0938 Brincidofovir Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir with long-acting antiviral effect, shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections.
S3711 Carbasalate Calcium Carbasalate calcium (Iromin, Alcacyl, Omegin, Rheomin, Solupsan) is an analgesic, antipyretic, and anti-inflammatory drug as well as a platelet aggregation inhibitor.
S3801 Sodium Lauryl Sulfoacetate Sodium Lauryl Sulfoacetate, the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis.
E1126 AFN-1252 AFN-1252 (Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI), inhibits all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of ≤0.12 μg/ml.
E1421 A2ti-1 A2ti-1 is a selective and high-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t) with IC50 of 24 μM. A2ti-1 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. It also prevents human papillomavirus type 16 (HPV16) infection.
S6442 Chlorphenesin Chlorphenesin is a synthetic preservative used in skin care as a cosmetic biocide.
S9342 1,4-Naphthoquinone 1,4-Naphthoquinone (α-Naphthoquinone, para-naphthoquinone, P-Naphthoquinone), found in diesel exhaust particles and it is an active metabolite of naphthalene, is a fumigant insecticide.
S2564 Cloxacillin Sodium Cloxacillin Sodium(Cloxacap,BRL 1621 sodium salt) is a sodium salt of cloxacillin that is a penicillinase-resistant, acid resistant, semi-synthetic penicillin.
J Immunother Cancer, 2024, 12(11)e009805
S9112 Kaempferitrin Kaempferitrin (Lespenefril, Lespedin, Lespenephryl, Kaempferol 3,7-dirhamnoside), isolated from the leaves of Hedyotis verticillata and from Onychium japonicum, has antimicrobial, antioxidant, and anti-inflammatory activities.
S9113 Ononin Ononin (Formononetin glucoside, Formononetin 7-O-glucoside) is an isoflavone glycoside with anti-inflammtory effects.
S9341 3,4-Dimethoxycinnamic acid 3,4-Dimethoxycinnamic acid (Caffeic acid dimethyl ether) is a bioavailable coffee component as a perspective anti-prion compound and bind potently to prion protein with a Kd of 405 nM.
S6458 Isavuconazonium sulfate Isavuconazonium sulfate (BAL8557-002), the prodrug of the active triazole Isavuconazole, is an orally active antifungal agent, using for invasive aspergillosis and mucormycosis.
S6459 Nifurtimox Nifurtimox (BAY-2502) is an antiprotozoal agent.
S4232 Nithiamide Nithiamide (CL 5279) is a non-5-nitroimidazole drugs.
S3618 Acetylspiramycin (ASPM) Acetylspiramycin (ASPM, Spiramycin II, Foromacidin B) is a macrolide antimicrobial agent.
E3740 Isodon serra Extract Isodon Serra Extract is obtained from Isodon serra (Maxim.) Hara, which processes antitumour, anti-angiogenic, analgesic, antitubercular, anti-inflammatory, antibacterial and anti-ischemic activities.
S4515 Ademetionine disulfate tosylate Ademetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease.
E3744 Prunella Vulgaris Extract Prunella Vulgaris Extract is obtained from Prunella vulgaris, which is a medicinal herb that has been used for centuries to treat infections and other illnesses
S4236 Proflavine Hemisulfate Proflavine Hemisulfate is a topical antiseptic by interchelating DNA, thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands.
S5212 Imidazolidinyl Urea Imidazolidinyl Urea (Imidurea) is an antimicrobial agent used as preservative in cosmetics.
S5210 Sulfamethazine Sodium Salt Sulfamethazine (Sulfadimethyldiazine) is a sulfanilamide anti-infective agent used in the lifestock industry.
S0443 Desciclovir Desciclovir (DCV, 6-Deoxyacyclovir, BW A515U) is a prodrug of the antiherpetic agent acyclovir (ACV) that converted into ACV by xanthine oxidase in humans.
S4678 Povidone iodine Povidone iodine (Betadine, PVP iodine, PVP-I, Isodine) is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. Povidone iodine displays excellent antibacterial activity against MRSA and MSSA strains with MICs of 31.25 mg/L and 7.82 mg/L, respectively. Povidone iodine is used as a topical antiseptic in surgery and for skin and mucous membrane infections, as well as as an aerosol.
S0889 Dixanthogen Dixanthogen is an ectoparasiticide.
S5405 Propylparaben Propylparaben (Propyl 4-hydroxybenzoate, Propyl p-hydroxybenzoate, nipasol), a natural substance found in many plants and some insects, is an antimicrobial, preservative and flavouring agent.
E4946New Tafenoquine Succinate Tafenoquine Succinate(WR 238605 Succinate, Etaquine, Krintafel) is an 8-aminoquinoline (8AQ) anti-malarial drug that kills both the liver and blood stages of the parasite, broadening its applicability for chemoprophylaxis to all species of malaria. It is specifically used for the prevention of Plasmodium vivax relapse.
E3772 Eyebright Extract Eyebright Extract is extracted from Herba Euphrasiae (Scrophulariaceae), which includes anti-inflammatory, antioxidant, antimicrobial, anticancer, antifungal, antiviral, hypotensive, hapatoprotector, anti-epileptic, and anti-catarrhal activities.
S6802 Etosalamide Etosalamide (Ethosalamide) is an anti-inflammatory drug with antipyretic and analgesics properties.
S3978 5-Phenyl-2,4-pentadienoic acid 5-Phenyl-2,4-pentadienoic acid (5-Phenylpenta-2,4-dienoic acid) is used as Synthetic building block, anti-malarial agent.
S5390 N-(Hytroxymethy)micotinamide N-(Hydroxymethyl)nicotinamide (Nikomethamide, Bilamid, N-hydroxymethylnicotinamide) is an antimicrobial agent.
S3261 Myrislignan Myrislignan, a lignan isolated from Myristica fragrans Houtt, possesses anti-inflammatory activities. Myrislignan inhibits interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α). Myrislignan significantly inhibits the expressions of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) dose-dependently in LPS-stimulated macrophage cells. Myrislignan inhibits the NF-κB signalling pathway activation.
Oxid Med Cell Longev, 2023, 2023:7098313
S5355 Piperaquine phosphate Piperaquine phosphate is an orally active bisquinolone antimalarial drug.
S9560 Anisodamine Hydrobromide Anisodamine (6-Hydroxyhyoscyamine) is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs).
S5005 Cefotiam hydrochloride Cefotiam hydrochloride (Halospor, Pansporin, Pansporine) is the hydrochloride salt form of cefotiam and has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
E0516 Nequinate Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections, also inhibits xanthine oxidoreductase (XOD) activity.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!
S1962 Sulphadimethoxine Sulphadimethoxine is a non-reducing glucuronide.
S4555 Carsalam Carsalam (Carbonylsalicylamide) is a nonsteroidal anti-inflammatory drug.
E1436 A2ti-2 A2ti-2 is a selective and low-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t)with an IC50 of 230 μM. It specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10 and also prevents human papillomavirus type 16 (HPV16) infection.
S4521 DEET DEET (N,N-Diethyl-meta-toluamide, diethyltoluamide) is a commen active ingredient insect repellent.
E2971 Influenza Hemagglutinin (HA) Peptide Influenza Hemagglutinin (HA) Peptide is a synthetic peptide with an amino acid sequence of N-Tyr-Pro-Tyr-Asp-Val-Pro-Asp-Tyr-Ala-C. It is extensively used to isolate, purify, detect, and track the protein of interest in cell biology and biochemistry. It is used for competing out the anti-HA antibody binding to HA-tagged fusion proteins in immunoassays. It may also be used to to elute HA-tagged fusion proteins from an affinity column of Monoclonal Anti-HA agarose.
S1958 Sulbactam Sulbactam(CP45899) is a beta-lactamase inhibitor with an average IC50 of 0.8 μM.
S5001 Tofacitinib (CP-690550) Citrate Tofacitinib citrate (CP-690550, Tasocitinib) is a novel inhibitor of JAK with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively. Tofacitinib citrate has anti-infection activity.
J Exp Clin Cancer Res, 2024, 43(1):64
Antimicrob Agents Chemother, 2024, 68(4):e0135023.
Front Oncol, 2024, 14:1386190
S4157 Chloroquine diphosphate Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. Chloroquine is also an inhibitor of toll-like receptors (TLRs).
Nat Commun, 2024, 15(1):1642
Cancer Lett, 2024, 604:217258
Phytomedicine, 2024, 135:156053
S4430 Hydroxychloroquine (HCQ) Sulfate Hydroxychloroquine (HCQ) Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.
Redox Biol, 2024, 75:103274
Phytomedicine, 2024, 10.1016/j.phymed.2023.155152
Breast Cancer Res, 2024, 26(1):33
S8279 Shikonin Shikonin, a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay. Shikonin exerts an anti-inflammatory effect by inhibiting tumor necrosis factor-α (TNF-α) and prevents activation of nuclear factor-κB (NF-κB) pathway via proteasome inhibition.
Elife, 2024, 12RP91141
Elife, 2024, 12RP91141
Mol Ther Methods Clin Dev, 2024, 32(3):101307
S8068 Chaetocin Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively. Chaetocin is an anticancer agent and inhibitor of thioredoxin reductase (TrxR).
Int J Mol Sci, 2024, 25(17)9215
PeerJ, 2024, 12:e17222
Asian Pac J Trop Bio, 2023;, 13(6): 268-276
S2572 Streptomycin sulfate Streptomycin sulfate(Phytomycin) is a sulfate salt of streptomycin that is a protein synthesis inhibitor.
Front. Oncol, 2023-, Volume 13
Front Oncol, 2023, 13:1118268
Transl Oncol, 2022, 26:101502
S7465 FTI 277 HCl FTI 277 HCl is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. FTI 277 HCl inhibits cell growth and induces apoptosis. FTI 277 HCl is effective in clearing HDV viremia.
Cancer Res, 2023, 83(13):2248-2261
PLoS Biol, 2021, 19(4):e3001134
Cell Struct Funct, 2021, 46(1):1-9
S5184 Dexamethasone palmitate Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone (DXM), is a glucocorticoid receptor agonist with a 47-fold lower affinity for the glucocorticoid receptor than DXM. Dexamethasone palmitate (DXP) exhibits anti-inflammatory activity.
Dis Model Mech, 2022, dmm.049109
Hematology, 2022, 27(1):32-42
S1553 Delafloxacin (ABT-492) Delafloxacin (ABT-492, RX-3341, WQ-3034) is a new fluoroquinolone against 155 aerobic and 171 anaerobic pathogens.
Molecules, 2023, 28(6)2820
Molecules, 2023, 28(6), 2820
S5927 Proguanil Proguanil (chlorguanide, chloroguanide) is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.
Int J Med Sci, 2022, 19(2):233-241
Sci Adv, 2021, 7(27)eabh3032
E0206 Ginkgetin

Ginkgetin is a biflavone from Ginkgo biloba leaves with anti-cancer, anti-inflammatory, anti-microbial, anti-adipogenic, and neuroprotective activities.

Biomed Pharmacother, 2022, 154:113628
S7867 Oleuropein Oleuropein is an antioxidant polyphenol isolated from olive leaf. Oleuropein exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. Oleuropein inhibits PPARγ activity. Oleuropein exerts anti-adipogenic effect through direct inhibition of PPARγ transcriptional activity. Oleuropein also inhibits aromatase. Oleuropein induces apoptosis. Phase 2.
Front Endocrinol (Lausanne), 2024, 15:1354435
J Med Virol, 2019, 91(8):1440-1447
S3226 Dehydroabietic acid Dehydroabietic acid (DAA, DHAA), a naturally occurring diterpene resin acid derived from coniferous plants such as Pinus and Picea, displays anti-inflammatory activity via suppression of Src-, Syk-, and TAK1-mediated pathways.
S4945 Ethacridine lactate Ethacridine lactate (Acrinol) is an aromatic organic compound based on acridine used as an antiseptic agent. Ethacridine lactate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.
S3308 Caftaric acid Caftaric acid (CA, Caffeoyl tartaric acid) is a natural product that shows anti-oxidant and anti-inflammatory effects.
S4946 2,3-Dihydroxybenzoic acid 2,3-Dihydroxybenzoic acid (Pyrocatechuic acid, 3-Hydroxysalicylic acid, Hypogallic acid) is a natural phenol found in Phyllanthus acidus and in the aquatic fern Salvinia molesta, also a product of human aspirin metabolism. It is a potentially useful iron-chelating drug and has antimicrobial properties.
E0626 AX 20017 AX 20017 is a small-molecule protein kinase G (PknG) inhibitor with an IC50 of 0.39 μM.
S4303 9-Aminoacridine 9-Aminoacridine (Aminacrine) is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator and a negative mode small molecule MALDI matrix.
S4417 Ceftaroline Fosamil

Ceftaroline fosamil (CX-0903, DSP-5990, PPI-0903, TAK-599, Teflaro, Zinforo) is a cephalosporin with activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA).

S0846 Euquinine Euquinine is generally used as a febrifuge, antimalarial, and tonic.
S6771 MAC-545496 MAC-545496 is a nanomolar glycopeptide-resistance-associated protein R(GraR) inhibitor with strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM). MAC-545496 can reverse β-lactam resistance in methicillin-resistant strains and synergize with CAMPs. MAC-545496 shows remarkable activity in macrophages and attenuates S. aureus virulence in a G. mellonella larvae infection model.
S3711 Carbasalate Calcium Carbasalate calcium (Iromin, Alcacyl, Omegin, Rheomin, Solupsan) is an analgesic, antipyretic, and anti-inflammatory drug as well as a platelet aggregation inhibitor.
E1126 AFN-1252 AFN-1252 (Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI), inhibits all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of ≤0.12 μg/ml.
E1421 A2ti-1 A2ti-1 is a selective and high-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t) with IC50 of 24 μM. A2ti-1 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. It also prevents human papillomavirus type 16 (HPV16) infection.
S9341 3,4-Dimethoxycinnamic acid 3,4-Dimethoxycinnamic acid (Caffeic acid dimethyl ether) is a bioavailable coffee component as a perspective anti-prion compound and bind potently to prion protein with a Kd of 405 nM.
S4515 Ademetionine disulfate tosylate Ademetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease.
S6802 Etosalamide Etosalamide (Ethosalamide) is an anti-inflammatory drug with antipyretic and analgesics properties.
S3261 Myrislignan Myrislignan, a lignan isolated from Myristica fragrans Houtt, possesses anti-inflammatory activities. Myrislignan inhibits interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α). Myrislignan significantly inhibits the expressions of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) dose-dependently in LPS-stimulated macrophage cells. Myrislignan inhibits the NF-κB signalling pathway activation.
Oxid Med Cell Longev, 2023, 2023:7098313
E0516 Nequinate Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections, also inhibits xanthine oxidoreductase (XOD) activity.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!
E1436 A2ti-2 A2ti-2 is a selective and low-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t)with an IC50 of 230 μM. It specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10 and also prevents human papillomavirus type 16 (HPV16) infection.
S1958 Sulbactam Sulbactam(CP45899) is a beta-lactamase inhibitor with an average IC50 of 0.8 μM.
E4872New Mefloquine Mefloquine(Lariam, WR-142490) is a quinoline antimalarial drug and an antagonist of K+ channel (KvQT1/minK) with an IC50 of ~1 μM. It is widely used in both the treatment and prophylaxis of Plasmodium falciparum malaria, and can prolong cardiac repolarization.
S3279 Polyphyllin B (Formosanin C) Polyphyllin B (Formosanin C, FC), a diosgenin saponin isolated from Paris formosana, is an immunomodulator with antitumor activity. Polyphyllin B (Formosanin C, FC) induces apoptosis.
Oncol Lett, 2021, 22(1):550
S3269 Acetylcorynoline Acetylcorynoline, a major alkaloid component derived from Corydalis bungeana which is a traditional Chinese medical herb, shows anti-inflammatory properties. Acetylcorynoline may decrease egl-1 expression to suppress apoptosis pathways and increase rpn5 expression to enhance the activity of proteasomes.
S3270 Genipin 1-O-beta-D-gentiobioside Genipin 1-O-beta-D-gentiobioside (GG, Genipin 1-β-D-gentiobioside, Genipin 1-gentiobioside, Genipin 1-β-gentiobioside, Genipin gentiobioside) is a bioactive iridoid glycoside isolated from Gardenia jasminoides Ellis (Zhizi in Chinese) that exhibits hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities.
E4872New Mefloquine Mefloquine(Lariam, WR-142490) is a quinoline antimalarial drug and an antagonist of K+ channel (KvQT1/minK) with an IC50 of ~1 μM. It is widely used in both the treatment and prophylaxis of Plasmodium falciparum malaria, and can prolong cardiac repolarization.
E6014New Primaquine Primaquine (Primachin), an 8-aminoquinoline, is an antimalarial agent and a potent gametocytocidal in falciparum malaria. It also prevents relapse in vivax and ovale malaria.
E4946New Tafenoquine Succinate Tafenoquine Succinate(WR 238605 Succinate, Etaquine, Krintafel) is an 8-aminoquinoline (8AQ) anti-malarial drug that kills both the liver and blood stages of the parasite, broadening its applicability for chemoprophylaxis to all species of malaria. It is specifically used for the prevention of Plasmodium vivax relapse.

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Tags: Anti-infection inhibitor|Anti-infection agonist|Anti-infection activator|Anti-infection inducer|Anti-infection antagonist|Anti-infection signaling pathway|Anti-infection assay kit