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Anti-infection

Anti-infection Products

All (149)
Anti-infection Inhibitors (31)
Anti-infection Antagonist (1)
Anti-infection Modulators (3)
New Anti-infection Products

Catalog No.	Product Name	Information	Product Use Citations
S5001	Tofacitinib (CP-690550) Citrate	Tofacitinib citrate (CP-690550, Tasocitinib) is a novel inhibitor of JAK with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively. Tofacitinib citrate has anti-infection activity.	J Exp Clin Cancer Res, 2024, 43(1):64 Antimicrob Agents Chemother, 2024, 68(4):e0135023. Front Oncol, 2024, 14:1386190
S4157	Chloroquine diphosphate	Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. Chloroquine is also an inhibitor of toll-like receptors (TLRs).	Nat Commun, 2024, 15(1):1642 Cancer Lett, 2024, 604:217258 Phytomedicine, 2024, 135:156053
S4430	Hydroxychloroquine (HCQ) Sulfate	Hydroxychloroquine (HCQ) Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.	Redox Biol, 2024, 75:103274 Phytomedicine, 2024, 10.1016/j.phymed.2023.155152 Breast Cancer Res, 2024, 26(1):33
S8279	Shikonin	Shikonin, a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay. Shikonin exerts an anti-inflammatory effect by inhibiting tumor necrosis factor-α (TNF-α) and prevents activation of nuclear factor-κB (NF-κB) pathway via proteasome inhibition.	Elife, 2024, 12RP91141 Elife, 2024, 12RP91141 Mol Ther Methods Clin Dev, 2024, 32(3):101307
S4592	SBE-β-CD	SBE-β-CD is a novel, chemically modified cyclodextrin with a structure designed to optimize the solubility and stability of drugs.	Nat Commun, 2024, 15(1):5703 Cell Death Differ, 2024, 10.1038/s41418-024-01316-3 Nat Commun, 2023, 14(1):2806
S8068	Chaetocin	Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively. Chaetocin is an anticancer agent and inhibitor of thioredoxin reductase (TrxR).	PeerJ, 2024, 12:e17222 Asian Pac J Trop Bio, 2023;, 13(6): 268-276 Cancer Cell, 2023, 41(6):1118-1133.e12
S2264	Artemether	Artemether (SM-224, CGP 56696) is an antimalarial for the treatment of resistant strains of falciparum malaria.	J Pers Med, 2022, 12(2)258 Hum Cell, 2022, 10.1007/s13577-022-00671-y Sci Rep, 2021, 11(1):14571
S2572	Streptomycin sulfate	Streptomycin sulfate(Phytomycin) is a sulfate salt of streptomycin that is a protein synthesis inhibitor.	Front. Oncol, 2023-, Volume 13 Front Oncol, 2023, 13:1118268 Transl Oncol, 2022, 26:101502
S7465	FTI 277 HCl	FTI 277 HCl is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. FTI 277 HCl inhibits cell growth and induces apoptosis. FTI 277 HCl is effective in clearing HDV viremia.	Cancer Res, 2023, 83(13):2248-2261 PLoS Biol, 2021, 19(4):e3001134 Cell Struct Funct, 2021, 46(1):1-9
S2479	Lincomycin HCl	Lincomycin hydrochloride (Lincocin, NSC 70731,U10149A) is the monohydrated salt of lincomycin, a substance produced by the growth of a member of the lincolnensis group of Streptomyces lincolnensis.	J Pers Med, 2022, 12(2)258 Hum Cell, 2022, 10.1007/s13577-022-00671-y Hum Cell, 2021, 10.1007/s13577-021-00639-4
S2613	Clorsulon	Clorsulon (MK-401,L631529) is used in the treatment of Fasciola hepatica infections in calves and sheep.	J Pers Med, 2022, 12(2)258 Hum Cell, 2022, 10.1007/s13577-022-00671-y Hum Cell, 2021, 34(6):1911-1918
S1282	Artemisinin	Artemisinin is a sesquiterpene endoperoxide which is a potent antimalarial agent.	Virus Res, 2024, 349:199448 Drug Des Devel Ther, 2023, 17:1679-1697 Cancer Cell, 2022, S1535-6108(22)00312-9
S4147	Azithromycin Dihydrate	Azithromycin Dihydrate(CP-62993 dihydrate) is an acid stable orally administered macrolide antimicrobial drug, structurally related to erythromycin.	J Cell Biochem, 2022, 10.1002/jcb.30213 Adv Ther (Weinh), 2020, 2000034 PLoS Comput Biol, 2020, 16(12):e1008489
S4420	Mefloquine HCl	Mefloquine HCl(Mefloquin hydrochloride) is a blood schizonticide by inhibiting hemozoin formation, used as an antimalarial drug.	Mol Med Rep, 2021, 23(1)40 bioRxiv, 2020, 2020/9/20.4.7.30734 Int J Parasitol Drugs Drug Resist, 2018, 8(2):331-340
S3649	Ceftazidime	Ceftazidime(GR20263) is a third-generation cephalosporin that has activity against Gram-negative bacilli, including Pseudomonas aeruginosa.	Pharmacol Res, 2024, 201:107096 ACS Infect Dis, 2023, 10.1021/acsinfecdis.3c00264 Molecules, 2023, 28(6)2820
S7896	Sodium Tauroursodeoxycholate (TUDC)	Sodium Tauroursodeoxycholate (TUDC) is a water soluble bile salt, used for the treatment of gallstones and liver cirrhosis.	iScience, 2024, 27(8):110598 Infect Immun, 2024, 92(8):e0030024 Microbiome, 2019, 7(1):145
S4237	Primaquine Diphosphate	Primaquine Diphosphate is a transmission-blocking anti-malarial clinically available, displaying a marked activity against gametocytes of all species of human malaria.	J Extracell Vesicles, 2024, 13(7):e12494 Front Pharmacol, 2021, 12:695009 Cell Syst, 2019, 8(2):97-108
S3941	Pinocembrin	Pinocembrin (Dihydrochrysin, Galangin flavanone, 5,7-Dihydroxyflavanone) is a major flavonoid molecule incorporated as multifunctional in the pharmaceutical industry. Its vast range of pharmacological activities has been well researched including antimicrobial, anti-inflammatory, antioxidant, and anticancer activities.	Neurol Res, 2022, 1-10 J Neuroinflammation, 2020, 17(1):337
S5184	Dexamethasone palmitate	Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone (DXM), is a glucocorticoid receptor agonist with a 47-fold lower affinity for the glucocorticoid receptor than DXM. Dexamethasone palmitate (DXP) exhibits anti-inflammatory activity.	Dis Model Mech, 2022, dmm.049109 Hematology, 2022, 27(1):32-42
S1553	Delafloxacin (ABT-492)	Delafloxacin (ABT-492, RX-3341, WQ-3034) is a new fluoroquinolone against 155 aerobic and 171 anaerobic pathogens.	Molecules, 2023, 28(6)2820 Molecules, 2023, 28(6), 2820
S5397	Chlorhexidine	Chlorhexidine is a disinfectant and topical anti-infective agent that is active against Gram-positive and Gram-negative organisms, facultative anaerobes, aerobes, and yeasts.	J Cell Mol Med, 2021, 10.1111/jcmm.16673 BMC Microbiol, 2020, 20(1):275
S2282	Cinchonidine	Cinchonidine is an alkaloid used in asymmetric synthesis in organic chemistry.	CNS Neurosci Ther, 2023, 10.1111/cns.14403 J Med Virol, 2019, 91(8):1440-1447
S5967	Berberine chloride hydrate	Berberine (Natural Yellow 18) chloride hydrate is a quaternary ammonium salt from the group of isoquinoline alkaloids. Berberine activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. Berberine chloride decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. Berberine chloride induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. Berberine chloride is a dual topoisomerase I and II inhibitor. Berberine chloride is also a potential autophagy modulator.	Front Biosci (Landmark Ed), 2022, 27(8):242 Front Pharmacol, 2021, 12:632201
S4192	Chlorquinaldol	Chlorquinaldol(Chloquinan) is an antimicrobial agent used for local antisepsy.	Biosensors (Basel), 2023, 13(6)571 Biosensors (Basel), 2023, 13(6)571 ACS Synth Biol, 2022, 11(8):2820-2828
S5961	Prednisolone disodium phosphate	Prednisolone disodium phosphate (Hydeltrasol, Prednisolone 21-phosphate disodium) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties that exerts late mitogenic and biphasic effects on resistant acute lymphoblastic leukemia cells.	J Immunotoxicol, 2021, 18(1):154-162 Eur J Rheumatol, 2021, 10.5152/eurjrheum.2021.20054
S4759	p-Coumaric Acid	p-Coumaric acid (4-Hydroxycinnamic acid, P-Hydroxycinnamic acid, 4-Coumaric acid, Trans-p-Coumaric acid, para-Coumaric Acid) is a hydroxy derivative of cinnamic acid found in a variety of edible plants and is reported to have antioxidant, anti-inflammatory, and antimicrobial activity.	Exp Ther Med, 2021, 21(5):503 J Nutr Biochem, 2015, 26(11):1379-84
S7411	Ascomycin (FK520)	Ascomycin (FK520, FR 900520, Immunomycin), an FK-506 analog, is a neutral macrolide immunosuppressant, which prevents rejection after an organ transplant. Phase 3.	Melanoma Res, 2020, 30(4):325-335 Virol Sin, 2019, 34(6):648-661
S5927	Proguanil	Proguanil (chlorguanide, chloroguanide) is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.	Int J Med Sci, 2022, 19(2):233-241 Sci Adv, 2021, 7(27)eabh3032
P1201	LL37 (Human cathelicidin)	LL37 (Human cathelicidin, Ropocamptide) is a cathelicidin-related antimicrobial peptide with potent chemotactic and immunomodulatory properties.	Biomed Pharmacother, 2023, 157:114091 Biomed Pharmacother, 2022, 153:113292
S3746	Lumefantrine	Lumefantrine (benflumetol) is an antimalarial agent used to treat acute uncomplicated malaria.	Antimicrob Agents Chemother, 2021, AAC.02137-20 ACS Infect Dis, 2020, 10.1021/acsinfecdis.0c00522
S9131	Punicalagin	Punicalagin, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects., Punicalagin, a major ellagitannin found in pomegranate extracts, has been shown to have antioxidant, anti-inflammatory, and anticancer effects.	SLAS Discov, 2024, S2472-5552(24)00007-8 Cell, 2020, 30;181(3):637-652.e15. Cell, 2020, 30;181(3):637-652e15
S4242	Cetrimonium Bromide (CTAB)	Cetrimonium Bromide (CTAB) is a known component of the broad-spectrum antiseptic cetrimide, which is a mixture of different quaternary ammonium salts.	Biochem Cell Biol, 2021, 10.1139/bcb-2020-0570 Micromachines (Basel), 2018, 9(6)
S9185	Nitidine Chloride	Nitidine Chloride, a benzophenanthridine alkaloid found in species of the genus Zanthoxylum, has an anti-malarial activity.	Int Immunopharmacol, 2021, 101(Pt A):108273 Front Cell Neurosci, 2020, 14:216
S3067	Chlorhexidine 2HCl	Chlorhexidine hydrochloride (NSC-185) is an antiseptic effective against a wide variety of gram-negative and gram-positive organisms.	BMC Microbiol, 2020, 20(1):275
S2537	Secnidazole	Secnidazole (Flagentyl, PM 185184, RP 14539) is a nitroimidazole anti-infective.	Microorganisms, 2022, 10(7)1421
S4195	Broxyquinoline	Broxyquinoline(Dibromohydroxyquinoline) is an antiprotozoal agent and able to release oxygen free radicals from the water in mucous membranes.	ACS Synth Biol, 2022, 11(8):2820-2828
S4196	Ethacridine lactate monohydrate	Ethacridine lactate monohydrate(Acrinol monohydrat) is an aromatic organic compound based on acridine used as an antiseptic agent.	Carcinogenesis, 2014, 35(12):2822-30
S4726	Lauric Acid	Lauric Acid (dodecanoic acid, N-Dodecanoic acid, Dodecylic acid) is a saturated medium-chain fatty acid with a 12-carbon backbone. Lauric acid is found naturally in various plant and animal fats and oils, and is a major component of coconut oil and palm kernel oil.	Nat Commun, 2023, 14(1):660
S6288	Chlorhexidine diacetate	Chlorhexidine diacetate (Hibitane diacetate) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.	BMC Microbiol, 2020, 20(1):275
S4041	Olsalazine Sodium	Olsalazine Sodium is an anti-inflammatory prodrug, which consists of two 5-ASA moieties linked by an azo bond.	Oncotarget, 2017, 8(1):228-237
S6185	Arachidonic acid	Arachidonic acid (Arachidonate) is an unsaturated, essential fatty acid found in animal and human fat as well as in the liver, brain, and glandular organs. It is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.,	Bone Res, 2022, 10(1):20
S4172	Cetylpyridinium Chloride	Cetylpyridinium chloride(CPC) is a cationic quaternary ammonium compound used as oropharyngeal antiseptic.	iScience, 2024, 27(8):110598 Int J Mol Sci, 2023, 24(11)9708
S2395	Rheochrysidin	Rheochrysidin (Physcione) is an anthraquinone from roots of Rheum officinale Baill.	ACS Chem Biol, 2015, 10.1021/cb5009487
S4081	Sulfacetamide Sodium	Sulfacetamide Sodium is an anti-biotic.	G3 (Bethesda), 2020, 4;10(5):1585-1597
S9387	Maackiain	Maackiain (Demethylpterocarpin) is a pterocarpan that is widely distributed in leguminous plants. It has anticancer and antimicrobial effects.	Int Immunopharmacol, 2022, 108:108710
S5096	SulfadiMethoxine sodium	Sulfadimethoxine (Sulfadimethoxydiazine) is a long-lasting sulfonamide antimicrobial agent used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections.	Cell Death Dis, 2018, 9(6):646
E0206	Ginkgetin	Ginkgetin is a biflavone from Ginkgo biloba leaves with anti-cancer, anti-inflammatory, anti-microbial, anti-adipogenic, and neuroprotective activities.	Biomed Pharmacother, 2022, 154:113628
S5214	Imidocarb dipropionate	Imidocarb is an antiprotozoal agent, used as dipropionate in the treatment of babesiosis and ehrlichiosis.	Nat Commun, 2017, 8(1):823
S7867	Oleuropein	Oleuropein is an antioxidant polyphenol isolated from olive leaf. Oleuropein exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. Oleuropein inhibits PPARγ activity. Oleuropein exerts anti-adipogenic effect through direct inhibition of PPARγ transcriptional activity. Oleuropein also inhibits aromatase. Oleuropein induces apoptosis. Phase 2.	Front Endocrinol (Lausanne), 2024, 15:1354435 J Med Virol, 2019, 91(8):1440-1447
S3220	Trigonelline	Trigonelline (Trigenolline) is a plant alkaloid and a major component of coffee and fenugreek with anti-degranulation, anti-diabetic, antioxidant, anti-inflammatory, and neuroprotective effects. Trigonelline inhibits FcεRI-mediated intracellular signaling pathways, such as phosphorylation of PLCγ1, PI3K, and Akt. Trigonelline (Trigenolline) also inhibits the microtubule formation in RBL-2H3 cells.	Biomed Pharmacother, 2021, 143:112204
S3279	Polyphyllin B (Formosanin C)	Polyphyllin B (Formosanin C, FC), a diosgenin saponin isolated from Paris formosana, is an immunomodulator with antitumor activity. Polyphyllin B (Formosanin C, FC) induces apoptosis.	Oncol Lett, 2021, 22(1):550
S1644	Nitrofural	Nitrofural (Nitrofurazone) is a topical anti-infective agent with an IC50 of 22.83 ± 1.2 μM. (Rat LD50 = 590 mg/kg)
S2469	Fleroxacin	Fleroxacin (Ro 23-6240,AM-833,Quinodis, Megalocin) is a new broad-spectrum fluoroquinolone.
S3116	Sulfathiazole	Sulfathiazole is an organosulfur compound that has been used as a short-acting sulfa drug.
S2511	Sulfadoxine	Sulfadoxine (Sulphadoxine) is an ultra-long-lasting sulfonamide with an IC50 of 249 μg/ml for P. vivax.
S4191	Betamipron	Betamipron (CS-443,N-Benzoyl-β-alanine) is a chemical compound which is used together with panipenem to inhibit panipenem uptake into the renal tubule and prevent nephrotoxicity.
S2612	Ribitol	Ribitol (Adonitol) is a crystalline pentose alcohol and is formed by the reduction of ribose which is occurs naturally in the plant Adonis vernalis.
E0524	Spinosad	Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete, is a biological neurotoxic insecticide with a broader action spectrum, targeting the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system.
E0525	Colistin	Colistin(Polymyxin E), a cyclic polypeptide antibiotic synthesized by Bacillus polymyxa subspecies colistinus Koyama, exerts antimicrobial activity by targeting at the bacterial cell membrane.
S3226	Dehydroabietic acid	Dehydroabietic acid (DAA, DHAA), a naturally occurring diterpene resin acid derived from coniferous plants such as Pinus and Picea, displays anti-inflammatory activity via suppression of Src-, Syk-, and TAK1-mediated pathways.
S4945	Ethacridine lactate	Ethacridine lactate (Acrinol) is an aromatic organic compound based on acridine used as an antiseptic agent. Ethacridine lactate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.
S9564	p-Hydroxy-cinnamic Acid	p-Hydroxy-cinnamic Acid has in vitro antimalarial activity and in vivo anti-osteoporotic properties.
E4872^New	Mefloquine	Mefloquine(Lariam, WR-142490) is a quinoline antimalarial drug and an antagonist of K+ channel (KvQT1/minK) with an IC50 of ~1 μM. It is widely used in both the treatment and prophylaxis of Plasmodium falciparum malaria, and can prolong cardiac repolarization.
S9094	Pogostone	Pogostone is one of the secondary metabolites from Pogostemon cablin (Blanco) Benth. (Lamiaceae), serving as the effective component of the antimicrobial activity.	J Ethnopharmacol, 2021, 278:114250
S3269	Acetylcorynoline	Acetylcorynoline, a major alkaloid component derived from Corydalis bungeana which is a traditional Chinese medical herb, shows anti-inflammatory properties. Acetylcorynoline may decrease egl-1 expression to suppress apoptosis pathways and increase rpn5 expression to enhance the activity of proteasomes.
S3270	Genipin 1-O-beta-D-gentiobioside	Genipin 1-O-beta-D-gentiobioside (GG, Genipin 1-β-D-gentiobioside, Genipin 1-gentiobioside, Genipin 1-β-gentiobioside, Genipin gentiobioside) is a bioactive iridoid glycoside isolated from Gardenia jasminoides Ellis (Zhizi in Chinese) that exhibits hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities.
S3308	Caftaric acid	Caftaric acid (CA, Caffeoyl tartaric acid) is a natural product that shows anti-oxidant and anti-inflammatory effects.
E3085	Dichroae Radix Extract	Dichroae Radix Extract is drawed from Dichroae radix, exhibits good clinical efficacy in treatments as an antimalarial, expectorant or antifebrile agent in Chinese medicine, and it also has an anticoccidial effect in chickens infected by coccidiosis when used alone or as the main herb to formulate a complex.
E3107	Andrographis Herba Extract	Andrographis Herba Extract is obtained from the aerial part of Andrographis paniculata (Burm. F.) Nees, has various activities including antimicrobial and antioxidant, antimalarial, antiangiogenic, anti-inflammatory, anti-diabetic, and in vitro α-glucosidase and α-amylase enzyme inhibitory activities.
S4142	Clopidol	Clopidol (WR 61112) is an antiprotozoal agent.
S5700	Phthalylsulfathiazole	Phthalylsulfathiazole (Sulfathalidine) is a broad-spectrum antimicrobial that can treat different types of infections including intestinal.	Med Oncol, 2024, 41(8):188
S6136	(±)-α-Bisabolol	α-bisabolol is a small, plant-derived, oily sesquiterpene alcohol with some anti-inflammatory and even anti-microbial properties.
S5757	Isoeugenol	Isoeugenol (4-Propenylguaiacol), an essential oil constituent of nutmeg, clove, and cinnamon, shows antimicrobial activity.
S0320	Cycloguanil hydrochloride	Cycloguanil hydrochloride, an active metabolite of proguanil, acts on malaria schizonts in erythrocytes and hepatocytes.
S4250	Sulfamethoxypyridazine	Sulfamethoxypyridazine (CL 13494) is a long-acting sulfonamide for treatment of Dermatitis herpetiformis.
S6173	Amylmetacresol	Amylmetacresol is an antiseptic used to treat infections of the mouth and throat.
S4946	2,3-Dihydroxybenzoic acid	2,3-Dihydroxybenzoic acid (Pyrocatechuic acid, 3-Hydroxysalicylic acid, Hypogallic acid) is a natural phenol found in Phyllanthus acidus and in the aquatic fern Salvinia molesta, also a product of human aspirin metabolism. It is a potentially useful iron-chelating drug and has antimicrobial properties.
S2271	Berberine chloride	Berberine chloride is a quaternary ammonium salt from the group of isoquinoline alkaloids. Berberine activates caspase 3 and caspase 8, cleavage of poly ADP-ribose polymerase (PARP) and the release of cytochrome c. Berberine chloride decreases the expression of c-IAP1, Bcl-2 and Bcl-XL. Berberine chloride induces apoptosis with sustained phosphorylation of JNK and p38 MAPK, as well as generation of the ROS. Berberine chloride is a dual topoisomerase I and II inhibitor. Berberine chloride is also a potential autophagy modulator.	Adv Healthc Mater, 2023, e2300591. Transl Oncol, 2023, 35:101712 J Biomol Struct Dyn, 2022, 1-11
S5475	Novaluron	Novaluron (Rimon) belongs to the class of insecticides called insect growth regulators with pesticide properties.
S3218	Amiloxate	Amiloxate (Amiloxiate, Isoamyl Methoxycinnamate, Isopentyl 4-methoxycinnamate, Isoamyl 4-methoxycinnamate, Isoamyl p-methoxycinnamate, Isopentyl p-methoxycinnamate) is EMA-approved chemical UV-filter used in cosmetics. Amiloxate is a cinnamic acid derivative with anti-inflammatory activity.
S5963	Sulfathiazole sodium	Sulfathiazole sodium, an antimicrobial agent, is an organosulfur compound that has been used as a short-acting sulfa drug.
S6243	Ethyl pyruvate	Ethyl pyruvate (CTI-01) is a simple aliphatic ester of pyruvic acid and has been shown to have robust neuroprotective effects via its anti-inflammatory, anti-oxidative, and anti-apoptotic functions.	BMC Gastroenterol, 2024, 24(1):245
S3695	Cystamine dihydrochloride	Cystamine dihydrochloride (Decarboxycystine, 2-Aminoethyl disulfide, 2,2'-Dithiobisethanamine) acts as an anti-infective agent, which is used in the treatment of urinary tract infections and also as a radiation-protective agent that interferes with sulfhydryl enzymes.
S4175	Sulfaguanidine	Sulfaguanidine is a sulfonamide used as an anti-infective agent.
S3787	Picroside I	Picroside I (6'-Cinnamoylcatalpol), an iridoid glycoside, is a hepatoprotective agent which is reported to be antimicrobial and used against hepatitis B.
S9016	Dipsacoside B	Dipsacoside B, extracted from the flowerbuds of Lonicera confusa DC, shows strong antimicrobial activity.
S5908	Garenoxacin	Garenoxacin (T-3811ME, BMS-284756) is a novel des-F(6) quinolone that has been shown to be effective in vitro against a wide range of clinically important pathogens, including gram-positive and gram-negative aerobes and anaerobes.
E3166	Fermented Blank Bean Extract	Fermented Blank Bean Extract is extracted from the fermented Phaseolus vulgaris L., and aids in protection of the human digestive tract, mainly the colon.
S4062	Ronidazole	Ronidazole is an antiprotozoal agent.
S4971	Buparvaquone	Buparvaquone (Butalex) is a second-generation hydroxynaphthoquinone related to parvaquone, with novel features that make it a promising compound for the therapy and prophylaxis of all forms of theileriosis.
S6761	Dalfopristin	Dalfopristin (RP54476) is a semi-synthetic analogue of ostreogyrcin A. Quinupristin/dalfopristin (Q/D) is a parental streptogramin with a spectrum of activity that includes Gram-positive pathogens, including those resistant to other classes of antimicrobial compounds.
S5292	Diazolidinyl urea	Diazolidinyl urea (Germall II) is an antimicrobial preservative used in cosmetics.
E3350	Goodyera kwangtungensis Tso. extract	Goodyera kwangtungensis Tso. Extract is obtained from Goodyera kwangtungensis C.L. Tso, the entire plant is used to improve the condition of the lungs and to clear phlegm.
S3210	3'-Hydroxy-4'-methoxyacetophenone	3'-Hydroxy-4'-methoxyacetophenone (Acetoisovanillone, Isoacetovanillone, Diosmin EP Impurity A) is an active P. spinosa extract with anti-inflammatory potential.
E0626	AX 20017	AX 20017 is a small-molecule protein kinase G (PknG) inhibitor with an IC50 of 0.39 μM.
S5887	Khellin	Khellin (Methafrone, Visammin, Ammivisnagen, Khellinorm, Medekellin, Viscardan, Kalangin), a compound isolated from the seeds of Ammi Visnaga Lam (Umbelliferae), is used to treat a variety of maladies.
E0820	OX02983	OX02983 is a novel anthelmintic agent, actives against both egg and adult stages of Trichuris parasites, immobilising whipworm and reducing the ability of embryonated *Trichuris muris* eggs to establish infection in the mouse host.
S4303	9-Aminoacridine	9-Aminoacridine (Aminacrine) is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator and a negative mode small molecule MALDI matrix.
S0146	Broxaldine	Broxaldine (Brobenzoxaldine, AL307) is an antiprotozoal drug and can be used in leprosy.
S4417	Ceftaroline Fosamil	Ceftaroline fosamil (CX-0903, DSP-5990, PPI-0903, TAK-599, Teflaro, Zinforo) is a cephalosporin with activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA).
S0846	Euquinine	Euquinine is generally used as a febrifuge, antimalarial, and tonic.
E2137	WAY-297407	WAY-297407 is a bioactive compound.
E0749	Coumalic acid	Coumalic acid is a valuable platform compound which can be prepared from malic acid, can be used in the flavours, fragrances and cosmetics industries, as polymer components, and as pharmaceutical scaffolds displaying anti-bronchial and -malarial activity.
S9084	Rhoifolin	Rhoifolin (Rhoifoloside, Apigenin 7-O-neohesperidoside, Apigenin-7-O-rhamnoglucoside), a natural glycoside of apigenin, has been obtained from the green leaves of Rhus succedanea and possesses a variety of significant biological activities including antioxidant, anti-inflammatory, antimicrobial, hepatoprotective and anticancer effects.
E3695	Hypericum japonicum Extract	Hypericum Japonicum Extract is obtained from the entire herb of Hypericum japonicum, has been widely used for the treatment of bacterial diseases, infectious hepatitis, acute and chronic hepatitis, gastrointestinal disorder, internal hemorrhage and tumour.
E2665	Tafenoquine	Tafenoquine (WR 238605) is an 8-aminoquinoline, used as an anti-malarial prophylactic agent.
S6771	MAC-545496	MAC-545496 is a nanomolar glycopeptide-resistance-associated protein R(GraR) inhibitor with strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM). MAC-545496 can reverse β-lactam resistance in methicillin-resistant strains and synergize with CAMPs. MAC-545496 shows remarkable activity in macrophages and attenuates S. aureus virulence in a G. mellonella larvae infection model.
E2812	Antimalarial agent 1	Antimalarial agent 1 is a potent antimalarial drug.
E0938	Brincidofovir	Brincidofovir (CMX001), the lipid-conjugated prodrug of Cidofovir with long-acting antiviral effect, shows activity against a broad spectrum of DNA viruses including cytomegalovirus (CMV), adenovirus (ADV), varicella zoster virus, herpes simplex virus, polyomaviruses, papillomaviruses, poxviruses, and mixed double-stranded DNA virus infections.
S3711	Carbasalate Calcium	Carbasalate calcium (Iromin, Alcacyl, Omegin, Rheomin, Solupsan) is an analgesic, antipyretic, and anti-inflammatory drug as well as a platelet aggregation inhibitor.
S3801	Sodium Lauryl Sulfoacetate	Sodium Lauryl Sulfoacetate, the active compound of the Houttuynia plant, is mainly used for treating purulent skin infections, respiratory tract infections, including pneumonia in elderly patients, and chronic bronchitis.
E1126	AFN-1252	AFN-1252 (Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI), inhibits all clinical isolates of **Staphylococcus aureus and Staphylococcus epidermidis** at concentrations of ≤0.12 μg/ml.
E1421	A2ti-1	A2ti-1 is a selective and high-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t) with IC50 of 24 μM. A2ti-1 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. It also prevents human papillomavirus type 16 (HPV16) infection.
S6442	Chlorphenesin	Chlorphenesin is a synthetic preservative used in skin care as a cosmetic biocide.
S9342	1,4-Naphthoquinone	1,4-Naphthoquinone (α-Naphthoquinone, para-naphthoquinone, P-Naphthoquinone), found in diesel exhaust particles and it is an active metabolite of naphthalene, is a fumigant insecticide.
S2564	Cloxacillin Sodium	Cloxacillin Sodium(Cloxacap,BRL 1621 sodium salt) is a sodium salt of cloxacillin that is a penicillinase-resistant, acid resistant, semi-synthetic penicillin.
S9112	Kaempferitrin	Kaempferitrin (Lespenefril, Lespedin, Lespenephryl, Kaempferol 3,7-dirhamnoside), isolated from the leaves of Hedyotis verticillata and from Onychium japonicum, has antimicrobial, antioxidant, and anti-inflammatory activities.
S9113	Ononin	Ononin (Formononetin glucoside, Formononetin 7-O-glucoside) is an isoflavone glycoside with anti-inflammtory effects.
S9341	3,4-Dimethoxycinnamic acid	3,4-Dimethoxycinnamic acid (Caffeic acid dimethyl ether) is a bioavailable coffee component as a perspective anti-prion compound and bind potently to prion protein with a Kd of 405 nM.
S6458	Isavuconazonium sulfate	Isavuconazonium sulfate (BAL8557-002), the prodrug of the active triazole Isavuconazole, is an orally active antifungal agent, using for invasive aspergillosis and mucormycosis.
S6459	Nifurtimox	Nifurtimox (BAY-2502) is an antiprotozoal agent.
S4232	Nithiamide	Nithiamide (CL 5279) is a non-5-nitroimidazole drugs.
S3618	Acetylspiramycin (ASPM)	Acetylspiramycin (ASPM, Spiramycin II, Foromacidin B) is a macrolide antimicrobial agent.
E3740	Isodon serra Extract	Isodon Serra Extract is obtained from Isodon serra (Maxim.) Hara, which processes antitumour, anti-angiogenic, analgesic, antitubercular, anti-inflammatory, antibacterial and anti-ischemic activities.
S4515	Ademetionine disulfate tosylate	Ademetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease.
E3744	Prunella Vulgaris Extract	Prunella Vulgaris Extract is obtained from Prunella vulgaris, which is a medicinal herb that has been used for centuries to treat infections and other illnesses
S4236	Proflavine Hemisulfate	Proflavine Hemisulfate is a topical antiseptic by interchelating DNA, thereby disrupting DNA synthesis and leading to high levels of mutation in the copied DNA strands.
S5212	Imidazolidinyl Urea	Imidazolidinyl Urea (Imidurea) is an antimicrobial agent used as preservative in cosmetics.
S5210	Sulfamethazine Sodium Salt	Sulfamethazine (Sulfadimethyldiazine) is a sulfanilamide anti-infective agent used in the lifestock industry.
S0443	Desciclovir	Desciclovir (DCV, 6-Deoxyacyclovir, BW A515U) is a prodrug of the antiherpetic agent acyclovir (ACV) that converted into ACV by xanthine oxidase in humans.
S4678	Povidone iodine	Povidone iodine (Betadine, PVP iodine, PVP-I, Isodine) is a stable chemical complex of polyvinylpyrrolidone (povidone, PVP) and elemental iodine. Povidone iodine displays excellent antibacterial activity against MRSA and MSSA strains with MICs of 31.25 mg/L and 7.82 mg/L, respectively. Povidone iodine is used as a topical antiseptic in surgery and for skin and mucous membrane infections, as well as as an aerosol.
S0889	Dixanthogen	Dixanthogen is an ectoparasiticide.
S5405	Propylparaben	Propylparaben (Propyl 4-hydroxybenzoate, Propyl p-hydroxybenzoate, nipasol), a natural substance found in many plants and some insects, is an antimicrobial, preservative and flavouring agent.
E4946^New	Tafenoquine Succinate	Tafenoquine Succinate(WR 238605 Succinate, Etaquine, Krintafel) is an 8-aminoquinoline (8AQ) anti-malarial drug that kills both the liver and blood stages of the parasite, broadening its applicability for chemoprophylaxis to all species of malaria. It is specifically used for the prevention of Plasmodium vivax relapse.
E3772	Eyebright Extract	Eyebright Extract is extracted from Herba Euphrasiae (Scrophulariaceae), which includes anti-inflammatory, antioxidant, antimicrobial, anticancer, antifungal, antiviral, hypotensive, hapatoprotector, anti-epileptic, and anti-catarrhal activities.
S6802	Etosalamide	Etosalamide (Ethosalamide) is an anti-inflammatory drug with antipyretic and analgesics properties.
S3978	5-Phenyl-2,4-pentadienoic acid	5-Phenyl-2,4-pentadienoic acid (5-Phenylpenta-2,4-dienoic acid) is used as Synthetic building block, anti-malarial agent.
S5390	N-(Hytroxymethy)micotinamide	N-(Hydroxymethyl)nicotinamide (Nikomethamide, Bilamid, N-hydroxymethylnicotinamide) is an antimicrobial agent.
S3261	Myrislignan	Myrislignan, a lignan isolated from Myristica fragrans Houtt, possesses anti-inflammatory activities. Myrislignan inhibits interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α). Myrislignan significantly inhibits the expressions of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) dose-dependently in LPS-stimulated macrophage cells. Myrislignan inhibits the NF-κB signalling pathway activation.	Oxid Med Cell Longev, 2023, 2023:7098313
S5355	Piperaquine phosphate	Piperaquine phosphate is an orally active bisquinolone antimalarial drug.
S9560	Anisodamine Hydrobromide	Anisodamine (6-Hydroxyhyoscyamine) is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs).
S5005	Cefotiam hydrochloride	Cefotiam hydrochloride (Halospor, Pansporin, Pansporine) is the hydrochloride salt form of cefotiam and has a broad spectrum of activity against both gram-positive and gram-negative microorganisms.
E0516	Nequinate	Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections, also inhibits xanthine oxidoreductase (XOD) activity.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!
S1962	Sulphadimethoxine	Sulphadimethoxine is a non-reducing glucuronide.
S4555	Carsalam	Carsalam (Carbonylsalicylamide) is a nonsteroidal anti-inflammatory drug.
E1436	A2ti-2	A2ti-2 is a selective and low-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t)with an IC50 of 230 μM. It specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10 and also prevents human papillomavirus type 16 (HPV16) infection.
S4521	DEET	DEET (N,N-Diethyl-meta-toluamide, diethyltoluamide) is a commen active ingredient insect repellent.
E2971	Influenza Hemagglutinin (HA) Peptide	Influenza Hemagglutinin (HA) Peptide is a synthetic peptide with an amino acid sequence of N-Tyr-Pro-Tyr-Asp-Val-Pro-Asp-Tyr-Ala-C. It is extensively used to isolate, purify, detect, and track the protein of interest in cell biology and biochemistry. It is used for competing out the anti-HA antibody binding to HA-tagged fusion proteins in immunoassays. It may also be used to to elute HA-tagged fusion proteins from an affinity column of Monoclonal Anti-HA agarose.
S1958	Sulbactam	Sulbactam(CP45899) is a beta-lactamase inhibitor with an average IC50 of 0.8 μM.
S5001	Tofacitinib (CP-690550) Citrate	Tofacitinib citrate (CP-690550, Tasocitinib) is a novel inhibitor of JAK with IC50 of 1 nM, 20 nM and 112 nM against JAK3, JAK2, and JAK1, respectively. Tofacitinib citrate has anti-infection activity.	J Exp Clin Cancer Res, 2024, 43(1):64 Antimicrob Agents Chemother, 2024, 68(4):e0135023. Front Oncol, 2024, 14:1386190
S4157	Chloroquine diphosphate	Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. Chloroquine is also an inhibitor of toll-like receptors (TLRs).	Nat Commun, 2024, 15(1):1642 Cancer Lett, 2024, 604:217258 Phytomedicine, 2024, 135:156053
S4430	Hydroxychloroquine (HCQ) Sulfate	Hydroxychloroquine (HCQ) Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.	Redox Biol, 2024, 75:103274 Phytomedicine, 2024, 10.1016/j.phymed.2023.155152 Breast Cancer Res, 2024, 26(1):33
S8279	Shikonin	Shikonin, a potent and specific Pyruvate kinase M2 (PKM2) inhibitor, is a major component of zicao (purple gromwell, the dried root of Lithospermum erythrorhizon), a Chinese herbal medicine with various biological activities. It is also an inhibitor of TMEM16A chloride channel activity using cell-based fluorescent-quenching assay. Shikonin exerts an anti-inflammatory effect by inhibiting tumor necrosis factor-α (TNF-α) and prevents activation of nuclear factor-κB (NF-κB) pathway via proteasome inhibition.	Elife, 2024, 12RP91141 Elife, 2024, 12RP91141 Mol Ther Methods Clin Dev, 2024, 32(3):101307
S8068	Chaetocin	Chaetocin, a natural product from Chaetomium species, is a histone methyltransferase inhibitor with IC50 of 0.8 μM, 2.5 μM and 3 μM for dSU(VAR)3-9, mouse G9a and Neurospora crassa DIM5, respectively. Chaetocin is an anticancer agent and inhibitor of thioredoxin reductase (TrxR).	PeerJ, 2024, 12:e17222 Asian Pac J Trop Bio, 2023;, 13(6): 268-276 Cancer Cell, 2023, 41(6):1118-1133.e12
S2572	Streptomycin sulfate	Streptomycin sulfate(Phytomycin) is a sulfate salt of streptomycin that is a protein synthesis inhibitor.	Front. Oncol, 2023-, Volume 13 Front Oncol, 2023, 13:1118268 Transl Oncol, 2022, 26:101502
S7465	FTI 277 HCl	FTI 277 HCl is a potent and selective farnesyltransferase (FTase) inhibitor with IC50 of 500 pM, about 100-fold selectivity over the closely related GGTase I. FTI 277 HCl inhibits cell growth and induces apoptosis. FTI 277 HCl is effective in clearing HDV viremia.	Cancer Res, 2023, 83(13):2248-2261 PLoS Biol, 2021, 19(4):e3001134 Cell Struct Funct, 2021, 46(1):1-9
S5184	Dexamethasone palmitate	Dexamethasone palmitate (DXP), a lipophilic prodrug of Dexamethasone (DXM), is a glucocorticoid receptor agonist with a 47-fold lower affinity for the glucocorticoid receptor than DXM. Dexamethasone palmitate (DXP) exhibits anti-inflammatory activity.	Dis Model Mech, 2022, dmm.049109 Hematology, 2022, 27(1):32-42
S1553	Delafloxacin (ABT-492)	Delafloxacin (ABT-492, RX-3341, WQ-3034) is a new fluoroquinolone against 155 aerobic and 171 anaerobic pathogens.	Molecules, 2023, 28(6)2820 Molecules, 2023, 28(6), 2820
S5927	Proguanil	Proguanil (chlorguanide, chloroguanide) is a prophylactic antimalarial drug. It inhibits the dihydrofolate reductase of plasmodia and thereby blocks the biosynthesis of purines and pyrimidines, which are essential for DNA synthesis and cell multiplication.	Int J Med Sci, 2022, 19(2):233-241 Sci Adv, 2021, 7(27)eabh3032
E0206	Ginkgetin	Ginkgetin is a biflavone from Ginkgo biloba leaves with anti-cancer, anti-inflammatory, anti-microbial, anti-adipogenic, and neuroprotective activities.	Biomed Pharmacother, 2022, 154:113628
S7867	Oleuropein	Oleuropein is an antioxidant polyphenol isolated from olive leaf. Oleuropein exerts antioxidant, anti-inflammatory and anti-atherogenic effects and suppresses the adipocyte differentiation in vitro. Oleuropein inhibits PPARγ activity. Oleuropein exerts anti-adipogenic effect through direct inhibition of PPARγ transcriptional activity. Oleuropein also inhibits aromatase. Oleuropein induces apoptosis. Phase 2.	Front Endocrinol (Lausanne), 2024, 15:1354435 J Med Virol, 2019, 91(8):1440-1447
S3226	Dehydroabietic acid	Dehydroabietic acid (DAA, DHAA), a naturally occurring diterpene resin acid derived from coniferous plants such as Pinus and Picea, displays anti-inflammatory activity via suppression of Src-, Syk-, and TAK1-mediated pathways.
S4945	Ethacridine lactate	Ethacridine lactate (Acrinol) is an aromatic organic compound based on acridine used as an antiseptic agent. Ethacridine lactate is also a poly(ADP-ribose) glycohydrolase (PARG) inhibitor.
S3308	Caftaric acid	Caftaric acid (CA, Caffeoyl tartaric acid) is a natural product that shows anti-oxidant and anti-inflammatory effects.
S4946	2,3-Dihydroxybenzoic acid	2,3-Dihydroxybenzoic acid (Pyrocatechuic acid, 3-Hydroxysalicylic acid, Hypogallic acid) is a natural phenol found in Phyllanthus acidus and in the aquatic fern Salvinia molesta, also a product of human aspirin metabolism. It is a potentially useful iron-chelating drug and has antimicrobial properties.
E0626	AX 20017	AX 20017 is a small-molecule protein kinase G (PknG) inhibitor with an IC50 of 0.39 μM.
S4303	9-Aminoacridine	9-Aminoacridine (Aminacrine) is a highly fluorescent dye used clinically as a topical antiseptic and experimentally as a mutagen, an intracellular pH indicator and a negative mode small molecule MALDI matrix.
S4417	Ceftaroline Fosamil	Ceftaroline fosamil (CX-0903, DSP-5990, PPI-0903, TAK-599, Teflaro, Zinforo) is a cephalosporin with activity against Gram-positive pathogens, including methicillin-resistant Staphylococcus aureus (MRSA).
S0846	Euquinine	Euquinine is generally used as a febrifuge, antimalarial, and tonic.
S6771	MAC-545496	MAC-545496 is a nanomolar glycopeptide-resistance-associated protein R(GraR) inhibitor with strong binding affinity to the full-length GraR protein (Kd ≤ 0.1 nM). MAC-545496 can reverse β-lactam resistance in methicillin-resistant strains and synergize with CAMPs. MAC-545496 shows remarkable activity in macrophages and attenuates S. aureus virulence in a G. mellonella larvae infection model.
S3711	Carbasalate Calcium	Carbasalate calcium (Iromin, Alcacyl, Omegin, Rheomin, Solupsan) is an analgesic, antipyretic, and anti-inflammatory drug as well as a platelet aggregation inhibitor.
E1126	AFN-1252	AFN-1252 (Debio 1452) is a potent inhibitor of enoyl-acyl carrier protein reductase (FabI), inhibits all clinical isolates of **Staphylococcus aureus and Staphylococcus epidermidis** at concentrations of ≤0.12 μg/ml.
E1421	A2ti-1	A2ti-1 is a selective and high-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t) with IC50 of 24 μM. A2ti-1 specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10. It also prevents human papillomavirus type 16 (HPV16) infection.
S9341	3,4-Dimethoxycinnamic acid	3,4-Dimethoxycinnamic acid (Caffeic acid dimethyl ether) is a bioavailable coffee component as a perspective anti-prion compound and bind potently to prion protein with a Kd of 405 nM.
S4515	Ademetionine disulfate tosylate	Ademetionine Disulfate Tosylate is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activity and has been used in treatment of chronic liver disease.
S6802	Etosalamide	Etosalamide (Ethosalamide) is an anti-inflammatory drug with antipyretic and analgesics properties.
S3261	Myrislignan	Myrislignan, a lignan isolated from Myristica fragrans Houtt, possesses anti-inflammatory activities. Myrislignan inhibits interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α). Myrislignan significantly inhibits the expressions of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) dose-dependently in LPS-stimulated macrophage cells. Myrislignan inhibits the NF-κB signalling pathway activation.	Oxid Med Cell Longev, 2023, 2023:7098313
E0516	Nequinate	Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections, also inhibits xanthine oxidoreductase (XOD) activity.This product has poor solubility, animal experiments are available, cell experiments please choose carefully!
E1436	A2ti-2	A2ti-2 is a selective and low-affinity inhibitor of annexin A2/S100A10 heterotetramer (A2t)with an IC50 of 230 μM. It specifically disrupts the protein-protein interaction (PPI) between A2 and S100A10 and also prevents human papillomavirus type 16 (HPV16) infection.
S1958	Sulbactam	Sulbactam(CP45899) is a beta-lactamase inhibitor with an average IC50 of 0.8 μM.
E4872^New	Mefloquine	Mefloquine(Lariam, WR-142490) is a quinoline antimalarial drug and an antagonist of K+ channel (KvQT1/minK) with an IC50 of ~1 μM. It is widely used in both the treatment and prophylaxis of Plasmodium falciparum malaria, and can prolong cardiac repolarization.
S3279	Polyphyllin B (Formosanin C)	Polyphyllin B (Formosanin C, FC), a diosgenin saponin isolated from Paris formosana, is an immunomodulator with antitumor activity. Polyphyllin B (Formosanin C, FC) induces apoptosis.	Oncol Lett, 2021, 22(1):550
S3269	Acetylcorynoline	Acetylcorynoline, a major alkaloid component derived from Corydalis bungeana which is a traditional Chinese medical herb, shows anti-inflammatory properties. Acetylcorynoline may decrease egl-1 expression to suppress apoptosis pathways and increase rpn5 expression to enhance the activity of proteasomes.
S3270	Genipin 1-O-beta-D-gentiobioside	Genipin 1-O-beta-D-gentiobioside (GG, Genipin 1-β-D-gentiobioside, Genipin 1-gentiobioside, Genipin 1-β-gentiobioside, Genipin gentiobioside) is a bioactive iridoid glycoside isolated from Gardenia jasminoides Ellis (Zhizi in Chinese) that exhibits hepatoprotective, anti-inflammatory, antioxidant, and antithrombotic activities.
E4872^New	Mefloquine	Mefloquine(Lariam, WR-142490) is a quinoline antimalarial drug and an antagonist of K+ channel (KvQT1/minK) with an IC50 of ~1 μM. It is widely used in both the treatment and prophylaxis of Plasmodium falciparum malaria, and can prolong cardiac repolarization.
E4946^New	Tafenoquine Succinate	Tafenoquine Succinate(WR 238605 Succinate, Etaquine, Krintafel) is an 8-aminoquinoline (8AQ) anti-malarial drug that kills both the liver and blood stages of the parasite, broadening its applicability for chemoprophylaxis to all species of malaria. It is specifically used for the prevention of Plasmodium vivax relapse.

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