2,3-Dihydroxybenzoic acid

Synonyms: Pyrocatechuic acid, O-Pyrocatechuic acid, 2-Pyrocatechuic acid, 3-Hydroxysalicylic acid, Hypogallic acid

2,3-Dihydroxybenzoic acid (Pyrocatechuic acid, 3-Hydroxysalicylic acid, Hypogallic acid) is a natural phenol found in Phyllanthus acidus and in the aquatic fern Salvinia molesta, also a product of human aspirin metabolism. It is a potentially useful iron-chelating drug and has antimicrobial properties.

CAS No. 303-38-8

Purity & Quality Control

Batch: S494601 DMSO]30 mg/mL]false]]]false]]]false Purity: 98%
98

2,3-Dihydroxybenzoic acid Related Products

Biological Activity

Description 2,3-Dihydroxybenzoic acid (Pyrocatechuic acid, 3-Hydroxysalicylic acid, Hypogallic acid) is a natural phenol found in Phyllanthus acidus and in the aquatic fern Salvinia molesta, also a product of human aspirin metabolism. It is a potentially useful iron-chelating drug and has antimicrobial properties.
In Vivo
In vivo 2,3-dihydroxyhenzoic acid (2,3-DHB) is an orally effective iron-chelating agent in hypertransfused rat. The iron excreted in response tc 2,3-DHB is excreted via the urine. The oral administration of 2,3-DHB decreases time absorption of iron (59FeCl3) by the gut. The LD5O of 2,3-DHB is greater than 3 g/kg in the rabbit. Rats and mice administered up to 600 mg/kg chronically have shown no signs of toxicity[1].
Animal Research Animal Models iron-overloaded rat (Sprague-Dawley rats)
Dosages 100 mg/kg
Administration orally

Chemical Information & Solubility

Molecular Weight 154.12 Formula

C7H6O4

CAS No. 303-38-8 SDF --
Smiles C1=CC(=C(C(=C1)O)O)C(=O)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 30 mg/mL ( (194.65 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


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In vivo
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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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