Home Microbiology Anti-infection chemical Colistin For research use only.

Colistin

Synonyms: Polymyxin E

Colistin(Polymyxin E), a cyclic polypeptide antibiotic synthesized by Bacillus polymyxa subspecies colistinus Koyama, exerts antimicrobial activity by targeting at the bacterial cell membrane.

Colistin Chemical Structure

Colistin Chemical Structure

CAS No. 1066-17-7

Purity & Quality Control

Batch: E052501 Water]100 mg/mL]false]DMSO]Insoluble]false]Ethanol]Insoluble]false Purity: 99%
99

Colistin Related Products

Biological Activity

Description Colistin(Polymyxin E), a cyclic polypeptide antibiotic synthesized by Bacillus polymyxa subspecies colistinus Koyama, exerts antimicrobial activity by targeting at the bacterial cell membrane.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06087536 Not yet recruiting
Hospital-acquired Bacterial Pneumonia|Ventilator-associated Bacterial Pneumonia
Omnix Medical Ltd
 January 2024 Phase 2
NCT05542446 Terminated
Colistin
St. Anne''s University Hospital Brno Czech Republic|Palacky University
 September 1 2022 Phase 4
NCT04775238 Unknown status
Nosocomial Infections
Sohag University
 February 27 2021 Not Applicable
NCT04208945 Unknown status
Pneumonia Ventilator-associated|Gram-Negative Pneumonia
University of Thessaly
 December 2019 Not Applicable

Chemical Information & Solubility

Molecular Weight 1155.43 Formula

C52H98N16O13
CAS No. 1066-17-7 SDF --
Smiles NA
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

Water : 100 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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