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Arachidonic acid

Name: Arachidonic acid
Brand: Selleck Chemicals
SKU: S6185
Rating: 5 (1 reviews)

Synonyms: Arachidonate

Catalog No.S6185 Purity:99.75%

Arachidonic acid (Arachidonate) is an unsaturated, essential fatty acid found in animal and human fat as well as in the liver, brain, and glandular organs. It is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.,

Arachidonic acid Chemical Structure

CAS No. 506-32-1

Purity & Quality Control

Batch: Purity: 99.75%

99.75

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Related Compound Libraries	Kinase Inhibitor Library FDA-approved Drug Library Natural Product Library Bioactive Compound Library-I Highly Selective Inhibitor Library	Click to Expand

Biological Activity

Description	Arachidonic acid (Arachidonate) is an unsaturated, essential fatty acid found in animal and human fat as well as in the liver, brain, and glandular organs. It is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.,

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2024-05-22)
NCT06274788	Not yet recruiting	Parenteral Nutrition Associated Liver Disease (PNALD)\|Essential Fatty Acid Deficiency\|Malnutrition\|Pediatric ALL	Fresenius Kabi	May 1 2024	Phase 4
NCT05788588	Active not recruiting	Parenteral Nutrition	Fujian Shengdi Pharmaceutical Co. Ltd.	April 28 2023	Phase 3
NCT04827251	Recruiting	Coronary Artery Disease	University of Sao Paulo\|Fundação de Amparo à Pesquisa do Estado de São Paulo	September 1 2022	Not Applicable
NCT05542147	Recruiting	Type 2 Diabetes\|Cardiovascular Diseases\|Pharmacogenomic Drug Interaction	Mario Luca Morieri\|University Hospital Padova	July 3 2022	Not Applicable

Chemical Information & Solubility

Molecular Weight	304.47	Formula	C₂₀H₃₂O₂
CAS No.	506-32-1	SDF	--
Density	0.922 g/mL at 25 °C
Smiles	CCCCCC=CCC=CCC=CCC=CCCCC(=O)O
Storage (From the date of receipt)	2 years -20°C(in the dark) liquid	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	2 years -20°C(in the dark) liquid		1 month-20°Cin solvent

In vitro
Batch:

Molecular Weight Calculator

In vivo Batch: Add solvents to the product individually and in order.					In vivo Formulation Calculator
	Clear solution	5% DMSO 1 95% Corn oil	2.5mg/ml (8.21mM)	Taking the 1 mL working solution as an example, add 50 μL of 50 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.	In vivo Formulation Calculator
Clear solution	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O	2.5mg/ml (8.21mM)	Taking the 1 mL working solution as an example, add 50 μL of 50 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.
Clear solution	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O	3.05mg/ml (10.02mM)	Taking the 1 mL working solution as an example, add 50 μL of 61 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.
Clear solution	5% DMSO 1 95% Corn oil	0.5mg/ml (1.64mM)	Taking the 1 mL working solution as an example, add 50 μL of 10 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.

Preparing Stock Solutions

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
=	×	×

Dilution Calculator Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
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