Home Immunology & Inflammation Immunology & Inflammation related chemical Lysionotin For research use only.

Lysionotin

Lysionotin is a natural flavonoid predominantly found in fewflower lysionotus herbs and possesses many pharmacological properties, such as antibacterial, anti-inflammatory, antihypertensive, and free radical scavenging activities.

Lysionotin Chemical Structure

Lysionotin Chemical Structure

CAS No. 152743-19-6

Purity & Quality Control

Batch: S387701 DMSO]68 mg/mL]false]]]false]]]false Purity: 99.89%
99.89

Lysionotin Related Products

Biological Activity

Description Lysionotin is a natural flavonoid predominantly found in fewflower lysionotus herbs and possesses many pharmacological properties, such as antibacterial, anti-inflammatory, antihypertensive, and free radical scavenging activities.
In vitro
In vitro Lysionotin is an efficient inhibitor of α-toxin expression and shows significant protection against S. aureus in vitro and in vivo[1].
Cell Research Cell lines A549 human lung epithelial cells
Concentrations 0-16 μg/ml
Incubation Time 5 h
Method A549 human lung epithelial cells (ATCC CCL 185) are maintained in DMEM supplemented with 10% fetal serum at 37 ℃ and seeded in 96-well plates at a density of approximately 2 × 104 cells per well. Then, the cells are cultured with 200 μl of bacteria with various concentrations of lysionotin and incubated for 5 h at 37 ℃. For LDH assays, the supernatants from wells are assessed for LDH release with the Cytotoxicity Detection Kit.

Chemical Information & Solubility

Molecular Weight 344.32 Formula

C18H16O7
CAS No. 152743-19-6 SDF Download Lysionotin SDF
Smiles COC1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C(=C3O2)OC)O)OC)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 68 mg/mL ( (197.49 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Lysionotin | Lysionotin supplier | purchase Lysionotin | Lysionotin cost | Lysionotin manufacturer | order Lysionotin | Lysionotin distributor