Spinosad

Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete, is a biological neurotoxic insecticide with a broader action spectrum, targeting the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system.

Spinosad Chemical Structure

Spinosad Chemical Structure

CAS No. 168316-95-8

Purity & Quality Control

Batch: E052401 Ethanol]50 mg/mL]false]DMSO]3 mg/mL]false]Water]Insoluble]false Purity: 99.31%
99.31

Spinosad Related Products

Signaling Pathway

Biological Activity

Description Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete, is a biological neurotoxic insecticide with a broader action spectrum, targeting the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system.
Targets
nAChRs [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02485717 Completed
Scabies
ParaPRO LLC|Concentrics Research
May 2 2017 Phase 3

Chemical Information & Solubility

Molecular Weight 731.96 Formula

C41H65NO10

CAS No. 168316-95-8 SDF --
Smiles NA
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

Ethanol : 50 mg/mL

DMSO : 3 mg/mL ( (4.09 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble


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In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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