Home Immunology & Inflammation Immunology & Inflammation related chemical Halcinonide For research use only.

Halcinonide

Synonyms: SQ-18566

Halcinonide(SQ-18566) is a high potency corticosteroid used in topical preparations as an anti-inflammatory agent.

Halcinonide Chemical Structure

Halcinonide Chemical Structure

CAS No. 3093-35-4

Purity & Quality Control

Halcinonide Related Products

Biological Activity

Description Halcinonide(SQ-18566) is a high potency corticosteroid used in topical preparations as an anti-inflammatory agent.
In vitro
In vitro

Halcinonide is used topically in the treatment of certain skin conditions. Halcinonide interacts with steroid cytoplasmic receptors to induce antiinflammatory actions.[1]
In Vivo
In vivo

Halcinonide cream (0.1%) results in a significant decrease in mean adhesion scores on both postoperative days 3 and 7 in the damaged surface of the cecum of Wistar rats, and the adhesion incidence is 43.3% for the therapy groups and 100% for controls. Halcinonide cream (0.1%) reduces the total numbers of intraperitoneal leukocytes from 270 millions to 120.73 millions on day 3 in the Wistar rats. [1]

Chemical Information & Solubility

Molecular Weight 454.96 Formula

C24H32ClFO5
CAS No. 3093-35-4 SDF Download Halcinonide SDF
Smiles CC1(OC2CC3C4CCC5=CC(=O)CCC5(C4(C(CC3(C2(O1)C(=O)CCl)C)O)F)C)C
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 91 mg/mL ( (200.01 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 5 mg/mL

Water : Insoluble


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In vivo
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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