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Technical Data
| Formula | C24H32ClFO5 |
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| Molecular Weight | 454.96 | CAS No. | 3093-35-4 | |
| Solubility (25°C)* | In vitro | DMSO | 91 mg/mL (200.01 mM) | |
| Ethanol | 5 mg/mL (10.98 mM) | |||
| Water | Insoluble | |||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. * Room temperature shipping (Stability testing shows this product can be shipped without any cooling measures.) |
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Biological Activity
| Description | Halcinonide(SQ-18566) is a high potency corticosteroid used in topical preparations as an anti-inflammatory agent. |
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| In vitro | Halcinonide is used topically in the treatment of certain skin conditions. Halcinonide interacts with steroid cytoplasmic receptors to induce antiinflammatory actions.[1] |
| In vivo | Halcinonide cream (0.1%) results in a significant decrease in mean adhesion scores on both postoperative days 3 and 7 in the damaged surface of the cecum of Wistar rats, and the adhesion incidence is 43.3% for the therapy groups and 100% for controls. Halcinonide cream (0.1%) reduces the total numbers of intraperitoneal leukocytes from 270 millions to 120.73 millions on day 3 in the Wistar rats. [1] |
Protocol (from reference)
RETURN POLICY
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SHIPPING AND STORAGE
Selleck products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Selleck Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Selleck products are stable under the recommended conditions.
NOT FOR HUMAN, VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.