Home Immunology & Inflammation Immunology & Inflammation related chemical Sasapyrine For research use only.

Sasapyrine

Synonyms: NSC-49171,Salsalate

Sasapyrine (Salsalate, NSC-49171) is a nonsteroidal oral anti-inflammatory agent.

Sasapyrine Chemical Structure

Sasapyrine Chemical Structure

CAS No. 552-94-3

Purity & Quality Control

Batch: S418801 DMSO]52 mg/mL]false]Ethanol]52 mg/mL]false]Water]Insoluble]false Purity: 99.2%
99.2

Sasapyrine Related Products

Biological Activity

Description Sasapyrine (Salsalate, NSC-49171) is a nonsteroidal oral anti-inflammatory agent.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03482440 Unknown status
Preeclampsia
University of Iowa|Penn State University
 August 26 2018 Early Phase 1
NCT03277573 Unknown status
Alzheimer Disease
Adam Boxer|University of California San Francisco
 July 21 2017 Phase 1
NCT01977417 Terminated
Prediabetes|Obese
Gary L. Pierce|University of Iowa
 November 2012 Phase 2
NCT01489319 Terminated
Polycystic Ovary Syndrome
Indiana University
 February 2012 Phase 1
NCT01182727 Completed
Schizophrenia|Insulin Resistance
University of Maryland Baltimore|US Department of Veterans Affairs
 August 2010 Not Applicable

Chemical Information & Solubility

Molecular Weight 258.23 Formula

C14H10O5
CAS No. 552-94-3 SDF Download Sasapyrine SDF
Smiles C1=CC=C(C(=C1)C(=O)OC2=CC=CC=C2C(=O)O)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 52 mg/mL ( (201.37 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 52 mg/mL

Water : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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