Home Immunology & Inflammation Immunology & Inflammation related chemical Imiquimod For research use only.

Imiquimod

Synonyms: R-837, S-26308

Imiquimod is a novel synthetic agent with immune response modifying activity.

Imiquimod Chemical Structure

Imiquimod Chemical Structure

CAS No. 99011-02-6

Purity & Quality Control

Imiquimod Related Products

Biological Activity

Description Imiquimod is a novel synthetic agent with immune response modifying activity.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06252857 Recruiting
Basal Cell Carcinoma
Maastricht University Medical Center
 April 22 2024 --
NCT06052696 Not yet recruiting
Vulvar HSIL|HPV
Erasmus Medical Center|Dutch Cancer Society
 December 1 2023 Phase 4
NCT05838599 Recruiting
Mycosis Fungoides
Northwestern University
 July 24 2023 Early Phase 1
NCT05315024 Unknown status
Influenza
The University of Hong Kong
 April 30 2022 Not Applicable
NCT04883645 Active not recruiting
Oral Cancer
Medical University of South Carolina
 April 28 2022 Early Phase 1

Chemical Information & Solubility

Molecular Weight 240.3 Formula

C14H16N4
CAS No. 99011-02-6 SDF Download Imiquimod SDF
Smiles CC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 2 mg/mL ( (8.32 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : Insoluble

Ethanol : Insoluble


Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

Preparing Stock Solutions

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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